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Genmab — September 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • SolsenS Offline
    SolsenS Offline
    Solsen
    wrote on sidst redigeret af
    #1521

    Lyt med i eftermiddag. Tror ikke platformen er beskrevet tidligere.

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    • O Offline
      O Offline
      OHW
      wrote on sidst redigeret af
      #1522

      Ok, tak.

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      • BulderB Offline
        BulderB Offline
        Bulder
        wrote on sidst redigeret af
        #1523

        This unique technology combines two HexaBody molecules designed to effectively and selectively hit only those cells that express both targets. The HexElect platform maximizes potency while minimizing potential toxicity.

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        • O Offline
          O Offline
          OHW
          wrote on sidst redigeret af
          #1524

          Bulder, ja jeg så det. Men hvad er target for midlet, ved du det? MM, solide eller?

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          • B Offline
            B Offline
            bibob
            wrote on sidst redigeret af
            #1525

            Dejligt at se JV 25/9 kl 21.24 stadig kan overraskes positivt over Genmab. ;-).

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            • BulderB Offline
              BulderB Offline
              Bulder
              wrote on sidst redigeret af
              #1526

              Det får vi nok at vide i eftermiddag.Men man kunne da forestille sig et bcma/cd38 i MM.

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              • B Offline
                B Offline
                bibob
                wrote on sidst redigeret af
                #1527

                Børsen. : udsigt til grøn åbning med Genmab i spidsen.

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                • G Offline
                  G Offline
                  gentogen
                  wrote on sidst redigeret af
                  #1528

                  Vi har tidligere set betegnelsen Hexabody Duobody (eller var det Duobody Hexabody)....

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                  • B Offline
                    B Offline
                    bibob
                    wrote on sidst redigeret af
                    #1529

                    Spidsen. - focus.

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #1530

                      Det var DuoHexabody. Og det er jo en bispecifik hexa

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                      • D Offline
                        D Offline
                        Doc4
                        wrote on sidst redigeret af
                        #1531

                        “Our cutting edge science and passion for innovation are at Genmab’s core. We are very excited to provide an update on the robust progress with our world-class innovative pipeline, as well as introducing HexElect, our novel next generation antibody therapeutics platform. This technology has been inspired by Genmab’s HexaBody technology and unlocks potency by making the action of two HexaBody molecules dependent on binding to two different targets on the same cell. ..

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                        • D Offline
                          D Offline
                          Doc4
                          wrote on sidst redigeret af
                          #1532

                          ...The technology has the potential to create leap-frog cancer therapeutic products with unprecedented efficacy and selectivity,” said Jan van de Winkel, Ph.D., Chief Executive Officer of Genmab.

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                          • O Offline
                            O Offline
                            OHW
                            wrote on sidst redigeret af
                            #1533

                            Tak Doc4

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                            • O Offline
                              O Offline
                              OHW
                              wrote on sidst redigeret af
                              #1534

                              Nå, marked går ikke i selvsving over den nyhed så vi må se med i aften..

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                              • JørgenVarnæsJ Offline
                                JørgenVarnæsJ Offline
                                JørgenVarnæs
                                wrote on sidst redigeret af
                                #1535

                                for duobody så vi at patentansøgningen røg afsted i 2007 og den optrådte første gang offentligt på en GEN-update I 2011. I går så vi første spæde tegn på klinisk effekt (nice find, by the way!)

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                                • JørgenVarnæsJ Offline
                                  JørgenVarnæsJ Offline
                                  JørgenVarnæs
                                  wrote on sidst redigeret af
                                  #1536

                                  Så der er vist ingen grund til at få knuder i trusserne endnu, fordi der bliver annonceret en ny teknologiplatform

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                                  • SolsenS Offline
                                    SolsenS Offline
                                    Solsen
                                    wrote on sidst redigeret af
                                    #1537

                                    Det er da spændene, at de bliver ved med at mene de kan forbedre deres teknologier.

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                                    • S Offline
                                      S Offline
                                      Sukkeralf
                                      wrote on sidst redigeret af
                                      #1538

                                      Det er jo den salgs der skal på banen, så Genmab på langt sigt kan vedblive med at være interessant - om platformen kan noget er umuligt for os at vallidere, så kursmæssigt giver det nok ikke alverden, før vi ser en partneraftale

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                                      • JørgenVarnæsJ Offline
                                        JørgenVarnæsJ Offline
                                        JørgenVarnæs
                                        wrote on sidst redigeret af
                                        #1539

                                        nøgleordet i start-up kredse er monetization

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                                        0
                                        • D Offline
                                          D Offline
                                          Doc4
                                          wrote on sidst redigeret af
                                          #1540

                                          JV...tror ikke din på din pessimisme..DuoBody->HexaBody->HexElect - der startes jo ikke forfra.. lidt lige som bil modeller;)

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                                          0

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