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Genmab — September 2018

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • O Offline
    O Offline
    OHW
    wrote on sidst redigeret af
    #1520

    Kan nogen med fagkendskab oplyse, hvad en HexElect antibody platform er? Tak på forhånd.

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    • SolsenS Offline
      SolsenS Offline
      Solsen
      wrote on sidst redigeret af
      #1521

      Lyt med i eftermiddag. Tror ikke platformen er beskrevet tidligere.

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      • O Offline
        O Offline
        OHW
        wrote on sidst redigeret af
        #1522

        Ok, tak.

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        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #1523

          This unique technology combines two HexaBody molecules designed to effectively and selectively hit only those cells that express both targets. The HexElect platform maximizes potency while minimizing potential toxicity.

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          • O Offline
            O Offline
            OHW
            wrote on sidst redigeret af
            #1524

            Bulder, ja jeg så det. Men hvad er target for midlet, ved du det? MM, solide eller?

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            • B Offline
              B Offline
              bibob
              wrote on sidst redigeret af
              #1525

              Dejligt at se JV 25/9 kl 21.24 stadig kan overraskes positivt over Genmab. ;-).

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              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #1526

                Det får vi nok at vide i eftermiddag.Men man kunne da forestille sig et bcma/cd38 i MM.

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                • B Offline
                  B Offline
                  bibob
                  wrote on sidst redigeret af
                  #1527

                  Børsen. : udsigt til grøn åbning med Genmab i spidsen.

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                  • G Offline
                    G Offline
                    gentogen
                    wrote on sidst redigeret af
                    #1528

                    Vi har tidligere set betegnelsen Hexabody Duobody (eller var det Duobody Hexabody)....

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                    • B Offline
                      B Offline
                      bibob
                      wrote on sidst redigeret af
                      #1529

                      Spidsen. - focus.

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #1530

                        Det var DuoHexabody. Og det er jo en bispecifik hexa

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                        • D Offline
                          D Offline
                          Doc4
                          wrote on sidst redigeret af
                          #1531

                          “Our cutting edge science and passion for innovation are at Genmab’s core. We are very excited to provide an update on the robust progress with our world-class innovative pipeline, as well as introducing HexElect, our novel next generation antibody therapeutics platform. This technology has been inspired by Genmab’s HexaBody technology and unlocks potency by making the action of two HexaBody molecules dependent on binding to two different targets on the same cell. ..

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                          • D Offline
                            D Offline
                            Doc4
                            wrote on sidst redigeret af
                            #1532

                            ...The technology has the potential to create leap-frog cancer therapeutic products with unprecedented efficacy and selectivity,” said Jan van de Winkel, Ph.D., Chief Executive Officer of Genmab.

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                            • O Offline
                              O Offline
                              OHW
                              wrote on sidst redigeret af
                              #1533

                              Tak Doc4

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                              • O Offline
                                O Offline
                                OHW
                                wrote on sidst redigeret af
                                #1534

                                Nå, marked går ikke i selvsving over den nyhed så vi må se med i aften..

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                                • JørgenVarnæsJ Offline
                                  JørgenVarnæsJ Offline
                                  JørgenVarnæs
                                  wrote on sidst redigeret af
                                  #1535

                                  for duobody så vi at patentansøgningen røg afsted i 2007 og den optrådte første gang offentligt på en GEN-update I 2011. I går så vi første spæde tegn på klinisk effekt (nice find, by the way!)

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                                  • JørgenVarnæsJ Offline
                                    JørgenVarnæsJ Offline
                                    JørgenVarnæs
                                    wrote on sidst redigeret af
                                    #1536

                                    Så der er vist ingen grund til at få knuder i trusserne endnu, fordi der bliver annonceret en ny teknologiplatform

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                                    • SolsenS Offline
                                      SolsenS Offline
                                      Solsen
                                      wrote on sidst redigeret af
                                      #1537

                                      Det er da spændene, at de bliver ved med at mene de kan forbedre deres teknologier.

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                                      • S Offline
                                        S Offline
                                        Sukkeralf
                                        wrote on sidst redigeret af
                                        #1538

                                        Det er jo den salgs der skal på banen, så Genmab på langt sigt kan vedblive med at være interessant - om platformen kan noget er umuligt for os at vallidere, så kursmæssigt giver det nok ikke alverden, før vi ser en partneraftale

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                                        • JørgenVarnæsJ Offline
                                          JørgenVarnæsJ Offline
                                          JørgenVarnæs
                                          wrote on sidst redigeret af
                                          #1539

                                          nøgleordet i start-up kredse er monetization

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