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Genmab — April 2015

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • R Offline
    R Offline
    Repsac
    wrote on sidst redigeret af
    #731

    så længe du ikke har købt ind for de 5 kr går det nok.

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    0
    • Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktør
      wrote on sidst redigeret af
      #732

      🙂 Jeg solgte i 539. Det blev så til 4 kr.:-)

      1 Reply Last reply
      0
      • Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktør
        wrote on sidst redigeret af
        #733

        535 er blevet testet to gange nu. Der strømmer pænt med købere til her.

        1 Reply Last reply
        0
        • G Offline
          G Offline
          gentogen
          wrote on sidst redigeret af
          #734

          Janine Schuurman, Ph.D., Vice President, Research, Genmab: Enhanced IgG Hexamerization Mediates Efficient C1q Docking and More Rapid and Substantial Complement-Dependent Cytotoxicity (CDC): Preclinical Proof of Concept.

          1 Reply Last reply
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          • G Offline
            G Offline
            gentogen
            wrote on sidst redigeret af
            #735

            We revealed that IgG antibodies form hexamers on the cell surface following antigen binding. These hexamers are critical for optimal C1q binding and CDC. IgG hexamerization occurs through specific non-covalent interactions between Fc-segments. We now identified mutations that enhanced IgG clustering after antigen binding to cells which led to an increase in C1q binding and CDC. Our data represent a promising novel approach for improving the efficacy of therapeutic antibodies.

            1 Reply Last reply
            0
            • G Offline
              G Offline
              gentogen
              wrote on sidst redigeret af
              #736

              Link Preview Image
              Engineering Antibodies at PEGS Summit | Protein & Antibody Engineering Summit 2026

              PEGS Engineering Antibodies conference offers a forum for discussing new technologies for overcoming complex engineering challenges including membrane-bound targets, agonism, and more.

              favicon

              Pegs Summit (www.pegsummit.com)

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              0
              • G Offline
                G Offline
                gentogen
                wrote on sidst redigeret af
                #737

                The DuoBody platform represents a novel and elegant post-production technology for the generation of stable bispecific antibodies. This platform is based on the easy-to-use method of controlled Fab-arm exchange and is used to generate bispecific antibodies that retain the biochemical characteristics and quality attributes of regular IgGs. The process has shown to be robust and scalable from bench (μg-mg) to mini bioreactor (mg-g) and manufacturing (kg) production.

                1 Reply Last reply
                0
                • G Offline
                  G Offline
                  gentogen
                  wrote on sidst redigeret af
                  #738

                  The presentation will highlight recent progress in terms of DuoBody discovery, proof-of-concepts, characterization and development.

                  1 Reply Last reply
                  0
                  • G Offline
                    G Offline
                    gentogen
                    wrote on sidst redigeret af
                    #739

                    Object moved

                    favicon

                    (www.pegsummit.com)

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                    • celsiusC Offline
                      celsiusC Offline
                      celsius
                      wrote on sidst redigeret af
                      #740

                      tusind tak Gentogen, du forstår som altid at bringe lys i mørket -:) .. og igen det blir en fantastisk måned maj 2015 .. pyha !!

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                      • celsiusC Offline
                        celsiusC Offline
                        celsius
                        wrote on sidst redigeret af
                        #741

                        det gælder om at holde på hat og briller .. det er blir nok den mest afgørende måned Genmabs´historie og går det godt så sør tør jeg slet ikke tænke på hvor kursen ender bare i år 2015

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                        0
                        • Helge_LarsenPI-redaktørH Offline
                          Helge_LarsenPI-redaktørH Offline
                          Helge_LarsenPI-redaktør
                          wrote on sidst redigeret af
                          #742

                          Tak Gentogen. 🙂

                          1 Reply Last reply
                          0
                          • celsiusC Offline
                            celsiusC Offline
                            celsius
                            wrote on sidst redigeret af
                            #743

                            Helge husk at skrive Genmab chatten -:) men ellers har du ret og tager det
                            skam heller ikke særlig tungt !

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                            0
                            • Helge_LarsenPI-redaktørH Offline
                              Helge_LarsenPI-redaktørH Offline
                              Helge_LarsenPI-redaktør
                              wrote on sidst redigeret af
                              #744

                              Jeg skriver i Genmabchatten, men min I-pad hakker den over i den forkerte chat nogen gange. 🙂

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                              0
                              • celsiusC Offline
                                celsiusC Offline
                                celsius
                                wrote on sidst redigeret af
                                #745

                                jeg víl hverken eje eller ha´en I-pad .. elsker min bærbar dell notebook Windows 7 .. det fås ikke bedre og det virker -:)

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                                0
                                • Helge_LarsenPI-redaktørH Offline
                                  Helge_LarsenPI-redaktørH Offline
                                  Helge_LarsenPI-redaktør
                                  wrote on sidst redigeret af
                                  #746

                                  136.000 stk har anonyme nu nettosolgt. De købte små 200.000 fredag og mandag.

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                                  0
                                  • J Offline
                                    J Offline
                                    JKY_VH
                                    wrote on sidst redigeret af
                                    #747

                                    fra sund fornuft til galimatias:-)

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                                    0
                                    • S Offline
                                      S Offline
                                      Sukkeralf
                                      wrote on sidst redigeret af
                                      #748

                                      Ja meget træls at man ikke kan se hvem præcist der købte og hvem der sælger

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                                      0
                                      • SolsenS Offline
                                        SolsenS Offline
                                        Solsen
                                        wrote on sidst redigeret af
                                        #749

                                        Ligner nogen der vidste ph3 var på vej med positive resultater og de sælger skuffede nu.

                                        1 Reply Last reply
                                        0
                                        • SolsenS Offline
                                          SolsenS Offline
                                          Solsen
                                          wrote on sidst redigeret af
                                          #750

                                          Men burde ikke være tilfældet...

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                                          0

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