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Genmab — April 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • G Offline
    G Offline
    GeorgeBest
    wrote on sidst redigeret af
    #907

    don't think, Jan van de Winkel gave up on one time milestones when he renegotiated the Arzerra deal

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    • G Offline
      G Offline
      GeorgeBest
      wrote on sidst redigeret af
      #908

      Genmab thereby got rid of participating in developement cost

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      • G Offline
        G Offline
        GeorgeBest
        wrote on sidst redigeret af
        #909

        it was in 2011 or so, when Genmab were in a very bad standing financially

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        • E Offline
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          E_L
          wrote on sidst redigeret af
          #910

          thanks. good memory 😉

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          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #911

            Det er gået under min radar, at Janssen kører kombi-studier i dara-talquetamab og dara-teclistamab i MM. Men betryggende at der holdes gang i dara-gryden. (Der er jo også hexa-cd38.) Når nu konkurrenter trænger sig på - Tak-079 og bela-m.

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            • S Offline
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              Sukkeralf
              wrote on sidst redigeret af
              #912

              Agree with GB on milestones for ofa i MS

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              • SolsenS Offline
                SolsenS Offline
                Solsen
                wrote on sidst redigeret af
                #913

                Jeg håber og tror på at de kombinationer de afprøver er gode. Mener at have set meget opmuntrene data fra dara og bcmaxcd3 kombinationen. Hvor jeg tænkte, at daras markedspotentiale kunne være truet fordi dara kun var med i indledende behandling. Men alt det ligger noget ud i fremtiden.

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                • SolsenS Offline
                  SolsenS Offline
                  Solsen
                  wrote on sidst redigeret af
                  #914

                  https://clincancerres.aacrjournals.org/content/clincanres/early/2020/03/23/1078-0432.CCR-19-2299.full.pdf Nu husker jeg ikke om denne er lagt op tidligere. Men her er synergien mellem dara og BCMAxCD3 beskrevet.

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #915

                    Tak solsen

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #916

                      so many articles on SC, just get it approved... https://www.reuters.com/article/multiple-myeloma-daratumumab/subcutaneous-daratumumab-effective-alternative-to-iv-formulation-for-multiple-myeloma-idUSL2N2BX1BJ

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                      • D Offline
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                        DevOp
                        wrote on sidst redigeret af
                        #917

                        Everyone at the FDA is working on the Remdesivir approval 😉

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                        • E Offline
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                          E_L
                          wrote on sidst redigeret af
                          #918

                          i think Dara will probable save more lives over time then Remdesivir, so they are wrong 😉

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                          • E Offline
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                            E_L
                            wrote on sidst redigeret af
                            #919

                            but seriously, FDA apparantly not really delayed very
                            much, still approving some drugs rather fast

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                            • D Offline
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                              DevOp
                              wrote on sidst redigeret af
                              #920

                              Cross fingers for tomorrow or Friday next week

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                              • E Offline
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                                E_L
                                wrote on sidst redigeret af
                                #921

                                Blood: A prospective phase 2 trial of daratumumab in patients with previously treated systemic light-chain amyloidosis https://ashpublications.org/blood/article-abstract/135/18/1531/452572/A-prospective-phase-2-trial-of-daratumumab-in

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #922

                                  Safety, tolerability, and response rates of daratumumab in relapsed AL amyloidosis: results of a phase 2 study https://ashpublications.org/blood/article-abstract/135/18/1541/440750/Safety-tolerability-and-response-rates-of

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                                  • B Offline
                                    B Offline
                                    bibob
                                    wrote on sidst redigeret af
                                    #923

                                    I like this line. https://ashpublications.org/blood/article-abstract/135/18/1509/454455/AL-patients-don-t-dare-go-without-dara?redirectedFrom=fulltext 🙂

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                                    • E Offline
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                                      E_L
                                      wrote on sidst redigeret af
                                      #924

                                      😄 JNJ should use that in their marketing lol

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                                      • E Offline
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                                        E_L
                                        wrote on sidst redigeret af
                                        #925

                                        YES!

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #926

                                          SC EUROPE

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