Genmab — April 2020
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don't think, Jan van de Winkel gave up on one time milestones when he renegotiated the Arzerra deal
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Genmab thereby got rid of participating in developement cost
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it was in 2011 or so, when Genmab were in a very bad standing financially
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Jeg håber og tror på at de kombinationer de afprøver er gode. Mener at have set meget opmuntrene data fra dara og bcmaxcd3 kombinationen. Hvor jeg tænkte, at daras markedspotentiale kunne være truet fordi dara kun var med i indledende behandling. Men alt det ligger noget ud i fremtiden.
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https://clincancerres.aacrjournals.org/content/clincanres/early/2020/03/23/1078-0432.CCR-19-2299.full.pdf Nu husker jeg ikke om denne er lagt op tidligere. Men her er synergien mellem dara og BCMAxCD3 beskrevet.
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so many articles on SC, just get it approved... https://www.reuters.com/article/multiple-myeloma-daratumumab/subcutaneous-daratumumab-effective-alternative-to-iv-formulation-for-multiple-myeloma-idUSL2N2BX1BJ
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Blood: A prospective phase 2 trial of daratumumab in patients with previously treated systemic light-chain amyloidosis https://ashpublications.org/blood/article-abstract/135/18/1531/452572/A-prospective-phase-2-trial-of-daratumumab-in
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Safety, tolerability, and response rates of daratumumab in relapsed AL amyloidosis: results of a phase 2 study https://ashpublications.org/blood/article-abstract/135/18/1541/440750/Safety-tolerability-and-response-rates-of
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