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Genmab — April 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #900

    Managing Multiple Myeloma During the COVID-19 Pandemic
    A Conversation With C. Ola Landgren https://www.ascopost.com/news/april-2020/managing-multiple-myeloma-during-the-covid-19-pandemic/

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    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #901

      Amivantamab er allerede på asco listen, så den er med på alm tilmelding. https://meetinglibrary.asco.org/session/12668

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #902

        we mentioned that yesterday already? also teclistamab

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        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #903

          Yes, it was meant for solsen 8:13

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #904

            ah, ok, of
            course

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #905

              i can find GBP65 mio in Cash proceeds related to ofatumumab milestone in the GSK presentation. Can Genmab expect any milestones?

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #906

                (they got that from Novartis)

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                • G Offline
                  G Offline
                  GeorgeBest
                  wrote on sidst redigeret af
                  #907

                  don't think, Jan van de Winkel gave up on one time milestones when he renegotiated the Arzerra deal

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                  • G Offline
                    G Offline
                    GeorgeBest
                    wrote on sidst redigeret af
                    #908

                    Genmab thereby got rid of participating in developement cost

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                    • G Offline
                      G Offline
                      GeorgeBest
                      wrote on sidst redigeret af
                      #909

                      it was in 2011 or so, when Genmab were in a very bad standing financially

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #910

                        thanks. good memory 😉

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #911

                          Det er gået under min radar, at Janssen kører kombi-studier i dara-talquetamab og dara-teclistamab i MM. Men betryggende at der holdes gang i dara-gryden. (Der er jo også hexa-cd38.) Når nu konkurrenter trænger sig på - Tak-079 og bela-m.

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #912

                            Agree with GB on milestones for ofa i MS

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                            • SolsenS Offline
                              SolsenS Offline
                              Solsen
                              wrote on sidst redigeret af
                              #913

                              Jeg håber og tror på at de kombinationer de afprøver er gode. Mener at have set meget opmuntrene data fra dara og bcmaxcd3 kombinationen. Hvor jeg tænkte, at daras markedspotentiale kunne være truet fordi dara kun var med i indledende behandling. Men alt det ligger noget ud i fremtiden.

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                              • SolsenS Offline
                                SolsenS Offline
                                Solsen
                                wrote on sidst redigeret af
                                #914

                                https://clincancerres.aacrjournals.org/content/clincanres/early/2020/03/23/1078-0432.CCR-19-2299.full.pdf Nu husker jeg ikke om denne er lagt op tidligere. Men her er synergien mellem dara og BCMAxCD3 beskrevet.

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #915

                                  Tak solsen

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #916

                                    so many articles on SC, just get it approved... https://www.reuters.com/article/multiple-myeloma-daratumumab/subcutaneous-daratumumab-effective-alternative-to-iv-formulation-for-multiple-myeloma-idUSL2N2BX1BJ

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                                    • D Offline
                                      D Offline
                                      DevOp
                                      wrote on sidst redigeret af
                                      #917

                                      Everyone at the FDA is working on the Remdesivir approval 😉

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #918

                                        i think Dara will probable save more lives over time then Remdesivir, so they are wrong 😉

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #919

                                          but seriously, FDA apparantly not really delayed very
                                          much, still approving some drugs rather fast

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