Genmab — Marts 2020
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Ja i tredie linie er det. Vincent Rajkumar har på Twitter meddelt at han vil bruge Sarclisa i Pom/Dex kombien hvis det er billigere...
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Sarclisa er kun godkendt til tredie linie plus patienter, så i første og anden linie er det ikke en trussel, og det er langt det største marked
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Nogen der ved hvornår Sarclisa kan blive godkendt i 1. og 2. linie?
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- linje dette her fase 3 - Ikema: https://www.clinicaltrials.gov/ct2/show/NCT03275285?term=isatuximab+mm&draw=2&rank=4
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Det eneste 1. linje jeg har kunnet finde er dette fase 1: https://www.clinicaltrials.gov/ct2/show/NCT02513186?term=isatuximab+mm&draw=2&rank=2
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Tak Bulder
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this NKTCL trial was recently completed; should we expect a Ph III trial to be started? https://clinicaltrials.gov/ct2/show/NCT02927925?term=NKTCL+AND+daratumumab&draw=2&rank=1
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There were some years ago stories about fantastic outcome for some patients with NKTCL who received dara. But since then it has been quite.
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Conclusions: DARA 16 mg/kg was well tolerated with no new safety concerns, and only 2 patients discontinuing due to TEAEs. DARA monotherapy demonstrated an encouraging response rate (ORR: 25%) in pts with R/R NKTCL and warrants further study in this poor prognosis pt population. https://ashpublications.org/blood/article/134/Supplement_1/1568/427350/Daratumumab-Monotherapy-for-Patients-with-Relapsed
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Genmab is proud to be on the 2020NJBIZ BestPlacesNJ to work list: https://njbiz.com/best-places-to-work-in-nj-2020/
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Se seneste slide ware fra Genmab side 33. DR5/DR5 er MEGET potent https://ir.genmab.com/static-files/50a5c114-5126-45a8-9d6f-17b883705a16
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