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Genmab — December 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • R Offline
    R Offline
    rolling
    wrote on sidst redigeret af
    #1060

    Bulder tror så ikke på de 10 mia i top omsætning??

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    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #1061

      Ikke allerede i 23 i hvert fald. Men topsalg på 8 mia er også nok. Det var jo det, man snakkede om oprindeligt, men så tog det fart med udsigter til dara i andre indikationer. Indtil videre ved vi ikke andet end at det ser lovende ud i amyloidosis.

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #1062

        it is fair to think Dara could be used in more applications. We have seen plenty of articles. By chance , Solsen mentioned yesterday he was surprised not to see more trials in other indications. But it will be JNJ that has to decide of the return on their investment in more trials is worth it. Their Dara investments and employees involved are already huge..

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #1063

          I also think it is 1 of the reasons why Jan will insist on 50-50 partnerships; it is not just about revenue; it is also about having
          control on how to proceed with a drug's development

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          • StockBullS Offline
            StockBullS Offline
            StockBull
            wrote on sidst redigeret af
            #1064

            forsent 11:15 hvorfor kun 25. Mange andre handles over 35 eksempelvis chr hansen, chemo m.m. Jo hvis Genmab kun har dara men med meget andet guf i piben ser jeg ikke nogen grund til Genmabs PE skal ned på 25 med mindre det er en one trick pony ?

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            • StockBullS Offline
              StockBullS Offline
              StockBull
              wrote on sidst redigeret af
              #1065

              11:15 = 11:51

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #1066

                and 35 = 53 😄

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                • StockBullS Offline
                  StockBullS Offline
                  StockBull
                  wrote on sidst redigeret af
                  #1067

                  Nemlig 😄

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                  • StockBullS Offline
                    StockBullS Offline
                    StockBull
                    wrote on sidst redigeret af
                    #1068

                    😄

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                    • J Offline
                      J Offline
                      JKY_VH
                      wrote on sidst redigeret af
                      #1069

                      Bulder 22:42, Jan svarer nok at Dara er mellem 2 og 100 gange bedre:-)

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                      • M Offline
                        M Offline
                        martinicph
                        wrote on sidst redigeret af
                        #1070

                        Ved et topsalg på 8 mia USD vil Dara generere et cashflow på 7,6 mia. DKK om året. Ved et salg på 3 mia USD i år vil royalty blive 2,3 mia USD (14,9 * 6,7 * 0,78). Ved topsalg om fem år og dernæst 10 års salg af Dara vil det give anslået ca. 100 mia. DKK i royalty, vel at mærke ikke tilbage diskonteret. Min konklusion: der skal inden da benhårde data
                        fra den øvrige pipeline, hvis PE 25+(altså om 5 år ikke nu) skal retfærdiggøres.

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                        • M Offline
                          M Offline
                          martinicph
                          wrote on sidst redigeret af
                          #1071

                          ... jeg mente 2,3 mia DKK i år (ikke USD)

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #1072

                            The Lancet - Quadruplets come of age for newly diagnosed multiple myeloma
                            Manisha Bhutani
                            Saad Z Usmani https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)33063-6/fulltext#section-7c530872-6235-4433-899c-b3f276970189 - https://sci-hub.tw/https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)33063-6/fulltext

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #1073

                              " A pertinent question is whether
                              the quadruplet therapy including daratumumab will
                              replace the current triplet therapy and alter clinical
                              practice to establish a new standard for transplantineligible, newly diagnosed multiple myeloma.

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #1074

                                Based
                                on favourable overall survival results of D-VMP, we
                                believe the future is already here, and the benefit of
                                adding daratumumab to a backbone of lenalidomide,
                                bortezomib, and dexamethasone will be clarified once
                                we have the mature results "

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                                • F Offline
                                  F Offline
                                  forsent
                                  wrote on sidst redigeret af
                                  #1075

                                  Stockbull. Jeg tænkte PE på 25 ud fra deres indtjening ville være svagt stigende om 4 år, ligesom Novo Nordisk f.eks. Deres PE er ca. 25. Men hvis der er udsigt til fald i indtjening, ligesom f.eks ved Novo og prispres i USA, så kan PE sagtens falde til 15. Men omvendt, er der udsigt til gode stigninger i indtjeningen, f.eks. 20-30% pr. år, så er PE sikkert 50. Det er utroligt svingende hvad PE er synes jeg, alt efter om der er udsigt til stigende eller faldende indtjeninger.

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                                  • F Offline
                                    F Offline
                                    forsent
                                    wrote on sidst redigeret af
                                    #1076

                                    Novo's PE røg lige under 15 da den var længst nede 🙂

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                                    • F Offline
                                      F Offline
                                      forsent
                                      wrote on sidst redigeret af
                                      #1077

                                      Noget helt andet: er der nogen der har bare en lille ide om hvad det teprotumumab kan omsætte for og hvad genmab får ud af det? samt hvad Tisotumumab kan opnå?

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #1078

                                        Horizon Q3 CC: We continue to estimate teprotumumab peak annual U.S. net sales of more than $750 million. Royalty satsen har vist været nævnt, men jeg kan ikke huske den.

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                                        • P Offline
                                          P Offline
                                          peter12
                                          wrote on sidst redigeret af
                                          #1079

                                          Det må være 5% ?

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