Genmab — December 2019
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Det er det vist ikke. Og det er fc-delen der bliver "silenced". Winkel skrev sidste år på q&a: You are referring to the way we have "silenced" the Fc-part of this bispecific. This has
been done in a novel manner with the intent of lessening interactions with immune
cells, resulting in less/absent non-specific activation of immune killer cells. This should
result in better safety. -
Go morgen.
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Update on MAIA study also provided as a poster. PFS still very good 68%) at 3 years. Even with Rd it was a median of 34. Effect of risk less clear on this dataset, although lower numbers.
https://twitter.com/Rfonsi1/status/1203433426101125120 -
Rafael Fonseca MD
@Rfonsi1
·
7 t
KEY PAPER. Updated FU on POLUX presented by @kaufman_MMdoc
. After a median FU of 59 months the median PFS reported at 45 months. Interestingly TTNT not reached after 63 months. https://twitter.com/Rfonsi1/status/1203437275213967377 -
The Debate Heats Up Over Treating High Risk Smoldering Multiple Myeloma
https://paper.li/Myeloma_Doc/1310386431?read=https%3A%2F%2Fwww.myelomacrowd.org%2Fash-2019-the-debate-heats-up-over-treating-high-risk-smoldering-multiple-myeloma%2F -
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Landgren previews pivotal ASH 2019 Myeloma data. https://www.onclive.com/conference-coverage/ash-2019/landgren-previews-pivotal-ash-2019-myeloma-data
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Tak bibo. Landgren giver en god oversigt.
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https://twitter.com/jacobplieth/status/1203294761123274754 Data på JNJ-4528
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