Genmab — Oktober 2018
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9:05..However, resistance of cancer cells to CDC is a major problem.
Two FDA-approved CD20 IgG1 mAbs, rituximab and ofatumumab,
promote only ∼15 and 50% CDC, respectively, of B cells from
patients with chronic lymphocytic leukemia (CLL)...we report that hexamerization-enhanced mAbs, specific for CD20
or CD37, induced 95–99% CDC of CLL B cells at concentrations of
10–16 g/mL in samples from 20 patients. CD37 mAbs without the
E430G mutation did not mediate CDC... -
Daratumumab in myeloma update: expanding indications, Niels van de Donk @ ESH - https://www.youtube.com/watch?v=66TVQeKcp38
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Update on recent smoldering multiple myeloma trials, Maria-Victoria Mateos @ESH https://www.youtube.com/watch?v=sF_fmbhnc0s
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CD38 antibodies under investigation for myeloma: isatuximab, MOR202 & TAK-079 https://www.youtube.com/watch?v=8-oiXhcegjw
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Updated CASTOR analysis: daratumumab plus Vd for R/R myeloma https://www.youtube.com/watch?v=2dwYLNTA19s
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ja det er imponerende
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og vi ved at Pollux er endnu bedre
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og 43% CR i 1.Relaps er det også mere end fint
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sorry 43
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Tusinde tak for link Bulder. http://www.proinvestor.com/index.php?p=debat_1&postid=76324
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Sorry E L. Right now I'm behind the counter in my shop in Rødovre Centrum. I am very busy and only look on the computer screen for a short while. I hope you can forgive me.
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Nyt stof: Daratutumab lovende mod Amyloidosis
https://www.youtube.com/watch?v=vTdWOZ5zCM8
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