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Genmab — Marts 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • SolsenS Offline
    SolsenS Offline
    Solsen
    wrote on sidst redigeret af
    #124

    Not surpricing lower they linalidomide in the maintenance settings from 15 mg to 10 mg. Long term treatment with linalidomide is trublesome.

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    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #125

      Most important is that they skip the transplant. Another sign that ASCT is loosing importance because of the novel highly effective therapies. And they now measure sCR during treatment but keep MRD-testing after treatment.

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      0
      • BulderB Offline
        BulderB Offline
        Bulder
        wrote on sidst redigeret af
        #126

        I guess that they have learned from Maria-Victoria Mateos' study that asct after all is a too rough treatment in the smoldering setting. http://www.ascopost.com/issues/january-25-2018/carfilzomib-based-treatment-and-transplant-in-smoldering-myeloma/

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        • Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktør
          wrote on sidst redigeret af
          #127

          God morgen. 🙂

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          0
          • B Offline
            B Offline
            bibob
            wrote on sidst redigeret af
            #128

            God morgen. 🙂

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            0
            • H Offline
              H Offline
              hda
              wrote on sidst redigeret af
              #129

              Godnat fra Guadeloupe 🙂

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              • P Offline
                P Offline
                pauly
                wrote on sidst redigeret af
                #130

                Godnat fra Køge 🙂

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                0
                • restenR Offline
                  restenR Offline
                  resten
                  wrote on sidst redigeret af
                  #131

                  God morgen iShares NASDAQ Biotechnology oppe med 2,44 % så vi håber & tror på en grøn dag selvom de har lovet hvid 🙂

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                  • B Offline
                    B Offline
                    bibob
                    wrote on sidst redigeret af
                    #132

                    God morgen. 🙂

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                    0
                    • P Offline
                      P Offline
                      Parasitism
                      wrote on sidst redigeret af
                      #133

                      God morgen 🙂

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                      0
                      • P Offline
                        P Offline
                        polle1
                        wrote on sidst redigeret af
                        #134

                        God morgen 🙂

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                        0
                        • V Offline
                          V Offline
                          Vitus
                          wrote on sidst redigeret af
                          #135

                          Så ser det ud til at der er hak i tuden til Genmab -:(

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #136

                            God morgen

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                            0
                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #137

                              Subcutaneous Daratumumab Potential Game Changer for Multiple Myeloma
                              Oncology Times: Feb 20, 2018 - https://journals.lww.com/oncology-times/Fulltext/2018/02200/Subcutaneous_Daratumumab_Potential_Game_Changer.18.aspx

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #138

                                might have been posterd before, but a few lines on how it is now admistered is interesting

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                                • S Offline
                                  S Offline
                                  Sukkeralf
                                  wrote on sidst redigeret af
                                  #139

                                  nice words: “This would be extremely practice-changing. Daratumumab has moved from monotherapy in advanced disease to first relapse. And now—at this year's ASH—we have newly diagnosed. That's a lot of dara[tumumab] being used globally. And to be giving a more convenient, potentially safer form of administration is really going to be very practice-changing.”

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                                  0
                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #140

                                    👍

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #141

                                      https://www.ncbi.nlm.nih.gov/pubmed/29500635?dopt=Abstract&utm_source=dlvr.it&utm_medium=twitter - Daratumumab augments alloreactive natural killer cell cytotoxicity towards CD38+ multiple myeloma cell lines in a biochemical context mimicking tumour microenvironment conditions. Don't try to read this before you had your coffee....

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #142

                                        ... and nice to know: The syringe pump is out of the picture with the 15 ml pre mixed vial. Could easily be administered at home by a nurse.

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                                        • Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktør
                                          wrote on sidst redigeret af
                                          #143

                                          😄

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                                          0

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