Genmab — Maj 2021

[E_L]

you did ask Jan some very difficult questions in the Q&A Bulder ; was that when the emails stopped ?

[Bulder]

Det lyder sandsynligt Mails er ikke for fattigrøve

[deleted-user]

15:10 - jeg må sidde tæt på serveren

[JørgenVarnæs]

Fattigrøve kan begynde her - https://ir.genmab.com/email-alert-subscription#content

[Bulder]

Tak JV. Jeg har ledt og ledt efter det.

[E_L]

Did we not assume roughly 10% market size for amyloidosis vs MM?

[deleted-user]

Pokkers. Var det ikke sidste år? God pinseferie til jer alle, når I kommer så langt,

[E_L]

the press release reads 'It is estimated that in 2019 there were 4,388 diagnosed incident cases of AL amyloidosis in the five major European markets.2'

[E_L]

So, lets assume easily >5.000 for whole western europe

[E_L]

'Approximately 18,114 new patients were diagnosed with multiple myeloma and approximately 11,063 people died from the disease in the Western Europe in 2020.'

[E_L]

that is not 10%...

[Bulder]

In my notes I have MM 27,8 bn $ and Amy 6,7 bn $.

[E_L]

that is much closer in %

[Bulder]

That is 2025-numbers

[JørgenVarnæs]

counting chickens, are we?

[E_L]

in the annual report , for the US, it was 32.270 people diagnosed MM, 4000 approximate in amyloid.

[E_L]

so that is 12.5%

[E_L]

the number of chickens are important to estimate the number of eggs.

[JørgenVarnæs]

Wasn’t the issue with Amy that because of the lack of treatment very few patients were diagnosed?

[E_L]

yes, and also because the symptoms aren't very obvious