Genmab — Februar 2021
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Troldmanden - har du styr på om en hexa-cd20 kunne være aktuel i cll? GEN fik vist rettighederne til cancer tilbage fra GSK
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hexa-cd20? Hvis du mener hexa-cd38 er svaret ja https://ir.genmab.com/news-releases/news-release-details/genmab-signs-agreement-janssen-next-generation-cd38-antibody/
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Det er måske epcoritamab, der er det primære program i det space? Umiddelbart mangler vi stadig PoC på hexa teknologien
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CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering - PubMed
CD20 monoclonal antibody therapies have significantly improved the outlook for patients with B-cell malignancies. However, many patients acquire resistance, demonstrating the need for new and improved drugs. We previously demonstrated that the natural process of antibody hexamer formation on targete …
PubMed (pubmed.ncbi.nlm.nih.gov)
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gad vide om det er en duo-hexa, de varmer op til der?
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det kunne tyde på, at den rene hexcd20 ikke ligger i kortene
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God morgen.
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Asien: Solide stigninger næsten overalt i regionen: https://www.proinvestor.com/investornyt/671857/asien-solide-stigninger-naesten-overalt-i-regionen
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Mandagens aviser med Carlsberg, Parken og Chr. Hansen: https://www.proinvestor.com/investornyt/671856/mandagens-aviser-med-carlsberg-parken-og-chr-hansen
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God morgen
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Genmab ligger stadig stabilt i trend kanalen fra Juni 2020 som indikere realistisk 12 mdr Genmab target 3000 kr https://nbg1.your-objectstorage.com/proinvestor-dev/forum/boards/90798_Interessandt_trend_fra_Juni_2020.JPG
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Treatment of Antibody-Mediated Post-Transplant Autoimmune-like Hepatitis with Daratumumab https://tct.confex.com/tct/2021/meetingapp.cgi/Paper/17519
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Conclusions
Now 10 months post-HCT, the patient is off all hepatic supportive care and steroids have gradually been weaned. He remains negative for minimal residual disease and BCR-ABL fusion transcript and 100% donor chimerism. The dramatic response documented in this patient warrants further investigation of daratumumab for plasma cell-mediated autoimmune-like hepatitis in the post-transplant setting.
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