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Genmab — December 2020

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #160

    Dr Mark Wildgust: Updated APOLLO Trial Results Confirm Daratumumab Safety in Multiple Myeloma https://www.ajmc.com/view/dr-mark-wildgust-updated-apollo-trial-results-confirm-daratumumab-safety-in-multiple-myeloma - ONLY
    5% of patients had infusion-related reactions in the APOLLO study, and all of those were grade 1/grade 2. So real confirmation that subcu dara is well tolerated.

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #161

      https://genmab-at-ash-2020.com/ genmab-at-ash-2020

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #162

        a bit strange when you look at the pipeline, poster on the right or https://virtualboothdemo.s3.amazonaws.com/Genmab/Content/PDFs/ash/I FINAL PIPELINE.pdf , it shows HexaBody CD38 in development phase I/II

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        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #163

          Must be because they plan to start one "soon".

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          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #164

            From August q&a: And are most excited and enthusiastic HexaBody-CD38 that is prepared for clinical
            production in the coming months as well.

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #165

              yes, i know it is supposed to come soon, i had hoped a bit just before ASH. But if it is not yet in the clinic, it is pre-clinical in my vocabulary 😉

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #166

                by the way, i also thought it was funny that Epco takes as much space on that page as Dara, Ofa and Tepezza together lol. How priorities
                change

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #167

                  Epco is the future. Tomorrow is as exciting as Sirius data in the past.

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                  • G Offline
                    G Offline
                    GeorgeBest
                    wrote on sidst redigeret af
                    #168

                    Talquetamab https://twitter.com/mohty_ebmt/status/1335139956205948929?s=21

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #169

                      yes, Sirius lol, that feels llike 100 years ago...

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #170

                        It is. 33% ORR, and we all went berserk. Never seen before 🙂

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #171

                          🙂 lets hope we have a simillar feeling this weekend

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #172

                            this is where i think we will be able to see everything, Materials will be available on a rolling basis as soon as individual embargoes are lifted. Dara has some lifted already https://www.oncologysciencehub.com/ash2020/

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #173

                              well not epco offourse only the JNJ stuff

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #174

                                Updated Phase 1 Results of Teclistamab https://www.oncologysciencehub.com/ash2020/bispecifics/garfall/#slides

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #175

                                  wasnt blenrep something like 35% ORR?

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                                  • G Offline
                                    G Offline
                                    GeorgeBest
                                    wrote on sidst redigeret af
                                    #176

                                    Nina Shah synes om Teclistamab https://twitter.com/ninashah33/status/1335327442563596289?s=21

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                                    • G Offline
                                      G Offline
                                      GeorgeBest
                                      wrote on sidst redigeret af
                                      #177

                                      Mange lignende kommentarer på Twitter, alle positive og „big advantage compared to CAR-T“

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                                      • P Offline
                                        P Offline
                                        peter12
                                        wrote on sidst redigeret af
                                        #178

                                        ORR er da tæt på 100% ved RP2D SC ? Jeg kan ikke finde 4 pts der ikke har respons ?

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #179

                                          Tiden går, klokken slår. Dara mono havde 33% ORR. Teclistamab 73% i RRMM

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