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Genmab — December 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #154

    Fra aftalen med Janssen: HexaBody-CD38 could be superior to daratumumab for certain tumor cell types and may expand and extend the promise of CD38-targeted therapies for more patients with multiple myeloma, lymphoma, leukemia, and potentially beyond.

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    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #155

      https://ir.genmab.com/news-releases/news-release-details/genmab-signs-agreement-janssen-next-generation-cd38-antibody/

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      • BulderB Offline
        BulderB Offline
        Bulder
        wrote on sidst redigeret af
        #156

        "beyond" kunne jo være solide?

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        • G Offline
          G Offline
          GeorgeBest
          wrote on sidst redigeret af
          #157

          Ja klart

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          • SolsenS Offline
            SolsenS Offline
            Solsen
            wrote on sidst redigeret af
            #158

            Hexa38 har præklinisk vist rigtig god effekt i DLBCL. Epco er også god her, men ellers en meget svær sygdom at kæmpe imod.

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #159

              https://twitter.com/HenrychihangFu1/status/1335039190845845504

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #160

                Dr Mark Wildgust: Updated APOLLO Trial Results Confirm Daratumumab Safety in Multiple Myeloma https://www.ajmc.com/view/dr-mark-wildgust-updated-apollo-trial-results-confirm-daratumumab-safety-in-multiple-myeloma - ONLY
                5% of patients had infusion-related reactions in the APOLLO study, and all of those were grade 1/grade 2. So real confirmation that subcu dara is well tolerated.

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #161

                  https://genmab-at-ash-2020.com/ genmab-at-ash-2020

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #162

                    a bit strange when you look at the pipeline, poster on the right or https://virtualboothdemo.s3.amazonaws.com/Genmab/Content/PDFs/ash/I FINAL PIPELINE.pdf , it shows HexaBody CD38 in development phase I/II

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #163

                      Must be because they plan to start one "soon".

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #164

                        From August q&a: And are most excited and enthusiastic HexaBody-CD38 that is prepared for clinical
                        production in the coming months as well.

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #165

                          yes, i know it is supposed to come soon, i had hoped a bit just before ASH. But if it is not yet in the clinic, it is pre-clinical in my vocabulary 😉

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #166

                            by the way, i also thought it was funny that Epco takes as much space on that page as Dara, Ofa and Tepezza together lol. How priorities
                            change

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #167

                              Epco is the future. Tomorrow is as exciting as Sirius data in the past.

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                              • G Offline
                                G Offline
                                GeorgeBest
                                wrote on sidst redigeret af
                                #168

                                Talquetamab https://twitter.com/mohty_ebmt/status/1335139956205948929?s=21

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #169

                                  yes, Sirius lol, that feels llike 100 years ago...

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #170

                                    It is. 33% ORR, and we all went berserk. Never seen before 🙂

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #171

                                      🙂 lets hope we have a simillar feeling this weekend

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #172

                                        this is where i think we will be able to see everything, Materials will be available on a rolling basis as soon as individual embargoes are lifted. Dara has some lifted already https://www.oncologysciencehub.com/ash2020/

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #173

                                          well not epco offourse only the JNJ stuff

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