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Genmab — September 2020

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
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    E_L
    wrote on sidst redigeret af
    #509

    Stephen L. Hauser, MD: Ofatumumab in Treatment-Naïve Patients With MS https://www.youtube.com/watch?v=Uz7OUaCIyfU

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    • E Offline
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      E_L
      wrote on sidst redigeret af
      #510

      Tisotumab data sets Seattle Genetics up for another approval, says Piper Sandler Piper Sandler analyst Joseph Catanzaro maintained a Neutral rating and $172 price target on SGen following the company's data from tisotumab's Phase II study in previously treated recurrent/metastatic cervical cancer at ESMO, which the analyst noted were "consistent with June's topline release." Catanzaro believes this data sets the company up for an "accelerated approval path in this setting for tisotumab."

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      • Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktør
        wrote on sidst redigeret af
        #511

        Great. Thanks E L. 🙂

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        • M Offline
          M Offline
          Mogan
          wrote on sidst redigeret af
          #512

          God morgen 🙂

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          • E Offline
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            E_L
            wrote on sidst redigeret af
            #513

            Blood Advances: Teclistamab is an active T cell–redirecting bispecific antibody against B-cell maturation antigen for multiple myeloma https://ashpublications.org/bloodadvances/article/4/18/4538/463776/Teclistamab-is-an-active-T-cell-redirecting

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            • E Offline
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              E_L
              wrote on sidst redigeret af
              #514

              it seems I was correct that a decision on Camidanlumab had to be taken this summer:

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                E_L
                wrote on sidst redigeret af
                #515

                ADCT looking to raise money again: ADC Therapeutics Announces Proposed Public Offering https://www.nasdaq.com/press-release/adc-therapeutics-announces-proposed-public-offering-2020-09-21

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                • E Offline
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                  E_L
                  wrote on sidst redigeret af
                  #516

                  which means we get a SEC report : https://sec.report/Document/0001140361-20-020981/#nt10014672x2_f1.htm

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                  • E Offline
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                    E_L
                    wrote on sidst redigeret af
                    #517

                    where on p6 it reads "Our collaboration and license agreement with Genmab may require a divestment of Cami, in which Genmab has a 25% interest. On June 24, 2020, we and Genmab agreed to enter into a period of good faith negotiations regarding the key financial terms of our license agreement. " etc etc

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                    • E Offline
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                      E_L
                      wrote on sidst redigeret af
                      #518

                      this may be a good Cami summary: "we are evaluating Cami in a 100-patient pivotal Phase 2 clinical trial for the treatment of relapsed or refractory HL and have enrolled 47 patients as of June 30, 2020.

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                      • E Offline
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                        E_L
                        wrote on sidst redigeret af
                        #519

                        We have completed enrollment of a 133-patient Phase 1 clinical trial of Cami for the treatment of relapsed or refractory HL and NHL that has shown an 86.5% ORR and a 48.6% CRR in patients with HL at the initial dose for our pivotal Phase 2 clinical trial and a 44.0% ORR and an 8.0% CRR in a subset of patients with T-cell lymphoma as of April 2019.

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                        • E Offline
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                          E_L
                          wrote on sidst redigeret af
                          #520

                          We anticipate reporting top-line response rate data from our pivotal Phase 2 clinical trial of Cami for the treatment of HL in the first half of 2021, and we believe that this clinical trial, if successful, will support a BLA submission.

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                          • E Offline
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                            E_L
                            wrote on sidst redigeret af
                            #521

                            We are also evaluating Cami in a Phase 1b clinical trial as a novel immuno-oncology approach for the treatment of various advanced solid tumors.

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                              E_L
                              wrote on sidst redigeret af
                              #522

                              More on the Collaboration and License Agreement is on p167 if interested

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                              • A Offline
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                                AaBforever
                                wrote on sidst redigeret af
                                #523

                                GENMAB/SHB: KURSMÅL HÆVES TIL 2400 KR. FRA 1920 KR./ritzau/FINANS

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                                • DarvinD Offline
                                  DarvinD Offline
                                  Darvin
                                  wrote on sidst redigeret af
                                  #524

                                  Det "lovede" de jo sådan set også den anden dag 🙂

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                                  • DarvinD Offline
                                    DarvinD Offline
                                    Darvin
                                    wrote on sidst redigeret af
                                    #525

                                    Men - de er slet ikke færdige

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                                    • S Offline
                                      S Offline
                                      Sukkeralf
                                      wrote on sidst redigeret af
                                      #526

                                      Good work again E L

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #527

                                        and finally in exhibit 10.6 it reeds "The Parties agree to negotiate for a period ending on 31 August 2020 with the intent to agree in good faith on a non-binding term sheet that includes all key financial terms for a license agreement between the Parties whereby ADCT acquires Genmab’s share of the ADC"

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #528

                                          so looks as if Genmab is trying to divest it

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