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Genmab — September 2020

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #456

    2 more twitter threads on Amivantamab, Stephen V Liu https://twitter.com/StephenVLiu/status/1307692420528832513 and Joshua Bauml https://twitter.com/Jbauml/status/1307839573435781120

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #457

      and since nobody bothered to correct my comment from yesterday evening (even thought i am sure you had all seen the mistake) ; i meant 2 Ph III trials for Amivantamab

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #458

        @Darvin for Mayo to start a trial is definately news. Really curious if it will be only for Lupus or also for other autoimmune diseases? The NEJM article attracted a surprisingly large number of positive comments from MDs on twitter over the last few days.

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #459

          ESMO: Janssen’s anti-EGFR combo tackles lung cancer ahead of phase 3 Tagrisso showdown https://www.fiercebiotech.com/biotech/esmo-janssen-s-anti-egfr-combo-tackles-lung-cancer-ahead-phase-3-tagrisso-showdown

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          • Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktør
            wrote on sidst redigeret af
            #460

            "The treatment beat back cancer in 20 newly diagnosed, never-before-treated patients, shrinking tumors in all of them. And in 45 patients whose disease had worsened despite taking Tagrisso, J&J’s treatment curbed tumor growth in 60% of them and shrank tumors in 36% of them. One patient had a complete response, meaning the drug eliminated all signs of cancer".

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            • Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktør
              wrote on sidst redigeret af
              #461

              Tak transalp og Pensionist:-)

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              • Helge_LarsenPI-redaktørH Offline
                Helge_LarsenPI-redaktørH Offline
                Helge_LarsenPI-redaktør
                wrote on sidst redigeret af
                #462

                Styrken er i top: https://www.proinvestor.com/investornyt/667040/6-c25-aktier-scorer-over-55-pa-styrkebarometer-genmab-i-top-58

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                • S Offline
                  S Offline
                  Sukkeralf
                  wrote on sidst redigeret af
                  #463

                  ATH

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                  • Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktør
                    wrote on sidst redigeret af
                    #464

                    🙂

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                    • DarvinD Offline
                      DarvinD Offline
                      Darvin
                      wrote on sidst redigeret af
                      #465

                      Tillykke og godt gået Helge 😄

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                      • DarvinD Offline
                        DarvinD Offline
                        Darvin
                        wrote on sidst redigeret af
                        #466

                        EL It was Rajkumar who announced It yesterday. And - depending on how you read the text - I read it as if they will open a trial for various autoimmune diseases - but only my way to read it

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #467

                          ok. we know Mayo has a Dara trial in CLL, in combination with Ibrutinib, will be interesting to see

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #468

                            Could be RA. Has been discussed before. I think Janssen has an unused IND for dara in RA. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932888/

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #469

                              https://twitter.com/TiansterZhang/status/1308023977483227137 Amgen showing bispecific CD3x PSMA , like JNJ-63898081

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                              • G Offline
                                G Offline
                                GeorgeBest
                                wrote on sidst redigeret af
                                #470

                                Genmab and Seattle Genetics Present Data from Tisotumab Vedotin
                                innovaTV 204 Pivotal Trial in Recurrent or Metastatic Cervical Cancer at
                                ESMO Virtual Congress 2020

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                                • G Offline
                                  G Offline
                                  GeorgeBest
                                  wrote on sidst redigeret af
                                  #471

                                  https://ir.genmab.com/news-releases/news-release-details/genmab-announces-janssen-has-submitted-supplemental-biologics

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                                  • G Offline
                                    G Offline
                                    GeorgeBest
                                    wrote on sidst redigeret af
                                    #472

                                    The results of the tisotumab vedotin phase 2 clinical trial are encouraging as they demonstrate clinically meaningful, durable responses with a manageable side effect profile

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #473

                                      correction for the link GB https://ir.genmab.com/news-releases/news-release-details/genmab-and-seattle-genetics-present-data-tisotumab-vedotin

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                                      • G Offline
                                        G Offline
                                        GeorgeBest
                                        wrote on sidst redigeret af
                                        #474

                                        thanks E L

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                                        • M Offline
                                          M Offline
                                          Macabo
                                          wrote on sidst redigeret af
                                          #475

                                          ORR 24% og DOR 8,3 måneder - det er godt men ikke knock of socks niveau

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