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Genmab — Juli 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • K Offline
    K Offline
    Klarussen
    wrote on sidst redigeret af
    #1000

    Ser teknisk svag ud på kort sigt efter 23. julis brud af optrendslinien fra midtmarts,
    støtte omkring 2000-området.

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    0
    • S Offline
      S Offline
      Sukkeralf
      wrote on sidst redigeret af
      #1001

      Så fik Jan ret i at CD3 var en dårlig kombi med CD38 ????

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      0
      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #1002

        not sure, when did he say that? JNJ is trying Dara with Teclistamab and Sanofi is experimenting with a tri-specific:
        Anti CD38-CD28-CD3

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        0
        • SolsenS Offline
          SolsenS Offline
          Solsen
          wrote on sidst redigeret af
          #1003

          JW said that CD3 was not the chosen combo with CD38. Dont remember why.

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          • SolsenS Offline
            SolsenS Offline
            Solsen
            wrote on sidst redigeret af
            #1004

            Remember some of us was worried that Xencor where chosen as bispecific partner by Amgen - Genmab is best in class 😉

            1 Reply Last reply
            0
            • J Offline
              J Offline
              Jedi
              wrote on sidst redigeret af
              #1005

              I don’t think a combo of two molecules (Dara and Teclistamab) can be compared to a single bispecific CD3 x CD38 agent

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              0
              • J Offline
                J Offline
                Jedi
                wrote on sidst redigeret af
                #1006

                ...and yes, good to see that Xencor did not have success with a bispecific that
                Gen is not pursuing:-)

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                • SolsenS Offline
                  SolsenS Offline
                  Solsen
                  wrote on sidst redigeret af
                  #1007

                  "World bispecific" har conference sidst i september og så vidt jeg kan se er Genmabs fravær påfaldende. Ydermere er der dagen op til en dag med særlig fokus på CD3 bispecifics https://bispecific.com/whats-on/agenda-at-a-glance/

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                  • J Offline
                    J Offline
                    Jedi
                    wrote on sidst redigeret af
                    #1008

                    On the Amivantamab trial note that the purpose is two-fold: In one part Lazertinib (arm C) is compared to Osimertinib (arm B), this part is blinded. In the other part Amivantamab is tested as add-on to Lazertinib (arm A) this part is open label, so JnJ can follow during the trial if this combo outperforms the blinded part, which is what we hope for

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                    • S Offline
                      S Offline
                      Sukkeralf
                      wrote on sidst redigeret af
                      #1009

                      The problem with CD38 is that it’s expressed many places in the body so activating the immune system there could be
                      troublesome

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                      0
                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #1010

                        Jedi - Yes combining dara with amivantamab is fine

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                        0
                        • SolsenS Offline
                          SolsenS Offline
                          Solsen
                          wrote on sidst redigeret af
                          #1011

                          Teclistamab 😉

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                          0
                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #1012

                            Åhhh ja da ????

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                            0
                            • S Offline
                              S Offline
                              Sukkeralf
                              wrote on sidst redigeret af
                              #1013

                              Hov min smiley blev til spørgsmålstegn

                              1 Reply Last reply
                              0
                              • Helge_LarsenPI-redaktørH Offline
                                Helge_LarsenPI-redaktørH Offline
                                Helge_LarsenPI-redaktør
                                wrote on sidst redigeret af
                                #1014

                                🙂 😄

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                                0
                                • Helge_LarsenPI-redaktørH Offline
                                  Helge_LarsenPI-redaktørH Offline
                                  Helge_LarsenPI-redaktør
                                  wrote on sidst redigeret af
                                  #1015

                                  Her fungerer det.

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                                  0
                                  • K Offline
                                    K Offline
                                    Klarussen
                                    wrote on sidst redigeret af
                                    #1016

                                    Så når vi snart 2200...

                                    1 Reply Last reply
                                    0
                                    • M Offline
                                      M Offline
                                      Mcjean
                                      wrote on sidst redigeret af
                                      #1017

                                      Falder altid 3 uger før regnskab hvor stoploss udløses og herefter stiger den mod regnskab, fordi deres regnskab altid er godt, ligesom NOVO's der bare buldre derud af med deres nye drug!

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                                      0
                                      • K Offline
                                        K Offline
                                        Klarussen
                                        wrote on sidst redigeret af
                                        #1018

                                        Hmm, håber du får ret. Ser frem til 12. august.

                                        1 Reply Last reply
                                        0
                                        • J Offline
                                          J Offline
                                          Joakim_Von_And
                                          wrote on sidst redigeret af
                                          #1019

                                          Må indrømme jeg har solgt lidt i dag... jeg kan ikke lide den corona,,, og dens konsekvenser.... som ingen kender omfanget af ....

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