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Genmab — Juli 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #1002

    not sure, when did he say that? JNJ is trying Dara with Teclistamab and Sanofi is experimenting with a tri-specific:
    Anti CD38-CD28-CD3

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    0
    • SolsenS Offline
      SolsenS Offline
      Solsen
      wrote on sidst redigeret af
      #1003

      JW said that CD3 was not the chosen combo with CD38. Dont remember why.

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      • SolsenS Offline
        SolsenS Offline
        Solsen
        wrote on sidst redigeret af
        #1004

        Remember some of us was worried that Xencor where chosen as bispecific partner by Amgen - Genmab is best in class 😉

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        • J Offline
          J Offline
          Jedi
          wrote on sidst redigeret af
          #1005

          I don’t think a combo of two molecules (Dara and Teclistamab) can be compared to a single bispecific CD3 x CD38 agent

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          0
          • J Offline
            J Offline
            Jedi
            wrote on sidst redigeret af
            #1006

            ...and yes, good to see that Xencor did not have success with a bispecific that
            Gen is not pursuing:-)

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            • SolsenS Offline
              SolsenS Offline
              Solsen
              wrote on sidst redigeret af
              #1007

              "World bispecific" har conference sidst i september og så vidt jeg kan se er Genmabs fravær påfaldende. Ydermere er der dagen op til en dag med særlig fokus på CD3 bispecifics https://bispecific.com/whats-on/agenda-at-a-glance/

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              • J Offline
                J Offline
                Jedi
                wrote on sidst redigeret af
                #1008

                On the Amivantamab trial note that the purpose is two-fold: In one part Lazertinib (arm C) is compared to Osimertinib (arm B), this part is blinded. In the other part Amivantamab is tested as add-on to Lazertinib (arm A) this part is open label, so JnJ can follow during the trial if this combo outperforms the blinded part, which is what we hope for

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                • S Offline
                  S Offline
                  Sukkeralf
                  wrote on sidst redigeret af
                  #1009

                  The problem with CD38 is that it’s expressed many places in the body so activating the immune system there could be
                  troublesome

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                  • S Offline
                    S Offline
                    Sukkeralf
                    wrote on sidst redigeret af
                    #1010

                    Jedi - Yes combining dara with amivantamab is fine

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                    0
                    • SolsenS Offline
                      SolsenS Offline
                      Solsen
                      wrote on sidst redigeret af
                      #1011

                      Teclistamab 😉

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                      0
                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #1012

                        Åhhh ja da ????

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                        0
                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #1013

                          Hov min smiley blev til spørgsmålstegn

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                          0
                          • Helge_LarsenPI-redaktørH Offline
                            Helge_LarsenPI-redaktørH Offline
                            Helge_LarsenPI-redaktør
                            wrote on sidst redigeret af
                            #1014

                            🙂 😄

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                            0
                            • Helge_LarsenPI-redaktørH Offline
                              Helge_LarsenPI-redaktørH Offline
                              Helge_LarsenPI-redaktør
                              wrote on sidst redigeret af
                              #1015

                              Her fungerer det.

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                              • K Offline
                                K Offline
                                Klarussen
                                wrote on sidst redigeret af
                                #1016

                                Så når vi snart 2200...

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                                • M Offline
                                  M Offline
                                  Mcjean
                                  wrote on sidst redigeret af
                                  #1017

                                  Falder altid 3 uger før regnskab hvor stoploss udløses og herefter stiger den mod regnskab, fordi deres regnskab altid er godt, ligesom NOVO's der bare buldre derud af med deres nye drug!

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                                  0
                                  • K Offline
                                    K Offline
                                    Klarussen
                                    wrote on sidst redigeret af
                                    #1018

                                    Hmm, håber du får ret. Ser frem til 12. august.

                                    1 Reply Last reply
                                    0
                                    • J Offline
                                      J Offline
                                      Joakim_Von_And
                                      wrote on sidst redigeret af
                                      #1019

                                      Må indrømme jeg har solgt lidt i dag... jeg kan ikke lide den corona,,, og dens konsekvenser.... som ingen kender omfanget af ....

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                                      • K Offline
                                        K Offline
                                        Klarussen
                                        wrote on sidst redigeret af
                                        #1020

                                        Der røg lige +32k i lukkeaktionen. Den var ellers ved at rette sig lidt. Det er lidt scarry med Corona-spøgelset, men Genmab burde ikke være så påvirket af det, jeg frygter snarere et stærkt fald hvis resten af markedet kollapser.

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                                        • SolsenS Offline
                                          SolsenS Offline
                                          Solsen
                                          wrote on sidst redigeret af
                                          #1021

                                          Mon ikke nogen benytter sommerferien til at få nogle til at ryste i bukserne. Måske 2100 er target ?

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                                          0

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