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Genmab — Maj 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • S Offline
    S Offline
    Sukkeralf
    wrote on sidst redigeret af
    #1239

    Could we get phase III data in amyloidosis with sc dara as a late breaker at EHA instead of ASCO?

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    • E Offline
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      E_L
      wrote on sidst redigeret af
      #1240

      it is possible, submission deadline for late breaker for
      EHA is about a month later i believe

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      • E Offline
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        E_L
        wrote on sidst redigeret af
        #1241

        I hope you are right on the epco deal for ASCO, but i am not sure Jan will feel much pressure ; we have been waiting soooo long; better get it right now...

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        • E Offline
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          E_L
          wrote on sidst redigeret af
          #1242

          Someone that knows him told me that, as nice as he is, he is actually a very very tough negotiator ...

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          • SolsenS Offline
            SolsenS Offline
            Solsen
            wrote on sidst redigeret af
            #1243

            Nice to hear 🙂

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            • E Offline
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              E_L
              wrote on sidst redigeret af
              #1244

              4544 / 12 - Multifaceted mechanism of action of DuoHexaBody-CD37 involves both complement- and Fc gamma receptor-mediated cytotoxicity in pre-clinical B-cell lymphoma models https://www.abstractsonline.com/pp8/#!/9045/presentation/7694

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #1245

                JNJ-61186372, an EGFR-cMet bispecific antibody, in EGFR Exon 20 insertion-driven advanced non-small cell lung cancer (NSCLC) https://www.abstractsonline.com/pp8/#!/9045/presentation/5116

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #1246

                  JNJ-61186372, an Fc enhanced EGFR/cMet bispecific antibody, mediates EGFR and cMet downmodulation and therapeutic efficacy preclinically through monocyte / macrophage mediated trogocytosis https://www.abstractsonline.com/pp8/#!/9045/presentation/7722

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #1247

                    JNJ-67571244: A novel anti-CD33 C2 domain binding bispecific antibody with potent T cell redirection activity https://www.abstractsonline.com/pp8/#!/9045/presentation/7733

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #1248

                      haven't heard much about the CD33xCD3 duobody yet

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                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #1249

                        i dont think so

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                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #1250

                          Its funny they promote these newer DuoBodies - not much we hear about JNJ-63709178. 1 or 2 clinical holds so maybe not much to look forward to here

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                          • E Offline
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                            E_L
                            wrote on sidst redigeret af
                            #1251

                            they did double the enrollment size not too long ago though on the -178 , that actually gave me little bit more hope 😉

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                            • E Offline
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                              E_L
                              wrote on sidst redigeret af
                              #1252

                              a few abstracts on BMS-986253
                              at ASCO (talking about something where i think there is not much to look forward to lol)

                              https://meetinglibrary.asco.org/results/986253?page=1

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                              • E Offline
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                                E_L
                                wrote on sidst redigeret af
                                #1253

                                @Mohty_EBMT
                                presented an argument FOR the integration of anti-CD38 antibodies into induction therapies. https://twitter.com/MM_Hub/status/1261257388159635456

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                                • S Offline
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                                  Sukkeralf
                                  wrote on sidst redigeret af
                                  #1254

                                  CD20/CD3 - måske postet før:

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                                  • S Offline
                                    S Offline
                                    Sukkeralf
                                    wrote on sidst redigeret af
                                    #1255

                                    Link Preview Image
                                    Bispecific Antibodies Poised to Impact Treatment of Lymphoma and Other Blood Cancers

                                    favicon

                                    (www.ascopost.com)

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #1256

                                      Tak sukker. Rart med samling på tingene 🙂

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #1257

                                        Educational theme | Monoclonal antibodies for the treatment of multiple myeloma https://multiplemyelomahub.com/medical-information/educational-theme-monoclonal-antibodies-for-the-treatment-of-multiple-myeloma

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                                        • SolsenS Offline
                                          SolsenS Offline
                                          Solsen
                                          wrote on sidst redigeret af
                                          #1258

                                          ADCs IPO i $19 https://finance.yahoo.com/m/aa62ce39-db78-3b7c-9bda-53e4c6e4d971/adc-therapeutics-prices-ipo.html

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