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Genmab — Februar 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #135

    Interesting that nsclc responded to pembro despite given dex as well. I wonder whether they should have chosen pembro in stead of atezo in the solid trial back then. Blocking PD-1 in stead of PD-L1?

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    • Legolas23L Offline
      Legolas23L Offline
      Legolas23
      wrote on sidst redigeret af
      #136

      Hvem ejer pembro. Også BMS?

      1 Reply Last reply
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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #137

        Maybe, but remember that the Pembro/Dara trial in MM was withdrawn a while back

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #138

          Pembrolizumab = Keytruda = Merck

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          • G Offline
            G Offline
            GeorgeBest
            wrote on sidst redigeret af
            #139

            Merck ejer pembro

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            • BulderB Offline
              BulderB Offline
              Bulder
              wrote on sidst redigeret af
              #140

              Yes but that was because of an IMiD, wasn't it?

              1 Reply Last reply
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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #141

                Recruitment Status : Withdrawn (Business Reasons) https://clinicaltrials.gov/ct2/show/NCT03221634

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #142

                  Lego: Atezo ejes af Roche. BMS ejer Opdivo - nivolumab

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #143

                    Nu vi snakker om BMS: "Den amerikanske medicinalkoncern Bristol-Myers Squibb, der for nyligt har gennemført det 74 mia. dollar store opkøb af biotekselskabet Celgene, har torsdag aflagt regnskab for fjerde kvartal, hvor indtjeningen overrasker positivt, mens prognoserne for 2020 er lidt til den svage side.
                    Aktien indikeres dog 3,0 pct. højere i det amerikanske formarked."

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #144

                      article by your local Dara / MM hero...

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #145

                        Controversy in the Use of CD38 Antibody for Treatment of Myeloma: Is High CD38 Expression Good or Bad? https://www.mdpi.com/2073-4409/9/2/378

                        1 Reply Last reply
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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #146

                          pdf
                          https://sci-hub.tw/https://www.mdpi.com/2073-4409/9/2/378

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #147

                            part of Special Issue "CD38 and Disease: A Bi-Directional Cross-Talk between Pathology and Physiology" https://www.mdpi.com/journal/cells/special_issues/CD38_CD157

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #148

                              I don't quite get the point here. Do they recommend a dara-break or not?

                              1 Reply Last reply
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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #149

                                i think they recomend more research before they can decide that...?

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #150

                                  it amazed me before, how much is still unknown about the workings of a drug that sells $3bn a year...

                                  1 Reply Last reply
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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #151

                                    this part has focus on CD38 in Solid Tumors https://www.mdpi.com/2073-4409/9/1/52/htm

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                                    • DarvinD Offline
                                      DarvinD Offline
                                      Darvin
                                      wrote on sidst redigeret af
                                      #152

                                      1637 - er det så rødvin igen. Det går altså ikke 😉

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                                      • SolsenS Offline
                                        SolsenS Offline
                                        Solsen
                                        wrote on sidst redigeret af
                                        #153

                                        🙂

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                                        • J Offline
                                          J Offline
                                          JKY_VH
                                          wrote on sidst redigeret af
                                          #154

                                          Du har ret Darvin, men på den anden side set så kunne der ske værre ting end at Genmab sætter endnu en kursrekord:-)

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