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Genmab — Februar 2020

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • J Offline
    J Offline
    JKY_VH
    wrote on sidst redigeret af
    #128

    haha 🙂

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    • Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktør
      wrote on sidst redigeret af
      #129

      5 år JKY. 😉

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      • J Offline
        J Offline
        JKY_VH
        wrote on sidst redigeret af
        #130

        som tiden dog går Helge:-)

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        • Legolas23L Offline
          Legolas23L Offline
          Legolas23
          wrote on sidst redigeret af
          #131

          Jeg ser det som sektor rotation pga coronavirusen væk fra berørte sektorer til bla medicinal. Jeg ser ingen hokus pokus i det. Der vil komme bump, korrektioner og andre besværligheder, men jeg er på ingen måder urolig.

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #132

            Durable response of multiple myeloma and non‐small cell lung cancer with simultaneous, biologically targeted treatment https://onlinelibrary.wiley.com/doi/full/10.1111/bjh.16393

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            • BulderB Offline
              BulderB Offline
              Bulder
              wrote on sidst redigeret af
              #133

              Thx E L. "Whether CD38 blockade on the lung tumour cells through daratumumab may have enhanced cytotoxic T‐cell function and contributed to the excellent response of the NSCLC to pembrolizumab, as recently reported for an in‐vivo model of lung cancer, is unknown (Chen et al., 2018)." But the idea is still alive.

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #134

                glad someone always reads these 😉

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #135

                  Interesting that nsclc responded to pembro despite given dex as well. I wonder whether they should have chosen pembro in stead of atezo in the solid trial back then. Blocking PD-1 in stead of PD-L1?

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                  • Legolas23L Offline
                    Legolas23L Offline
                    Legolas23
                    wrote on sidst redigeret af
                    #136

                    Hvem ejer pembro. Også BMS?

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #137

                      Maybe, but remember that the Pembro/Dara trial in MM was withdrawn a while back

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #138

                        Pembrolizumab = Keytruda = Merck

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                        • G Offline
                          G Offline
                          GeorgeBest
                          wrote on sidst redigeret af
                          #139

                          Merck ejer pembro

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #140

                            Yes but that was because of an IMiD, wasn't it?

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #141

                              Recruitment Status : Withdrawn (Business Reasons) https://clinicaltrials.gov/ct2/show/NCT03221634

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #142

                                Lego: Atezo ejes af Roche. BMS ejer Opdivo - nivolumab

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #143

                                  Nu vi snakker om BMS: "Den amerikanske medicinalkoncern Bristol-Myers Squibb, der for nyligt har gennemført det 74 mia. dollar store opkøb af biotekselskabet Celgene, har torsdag aflagt regnskab for fjerde kvartal, hvor indtjeningen overrasker positivt, mens prognoserne for 2020 er lidt til den svage side.
                                  Aktien indikeres dog 3,0 pct. højere i det amerikanske formarked."

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #144

                                    article by your local Dara / MM hero...

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #145

                                      Controversy in the Use of CD38 Antibody for Treatment of Myeloma: Is High CD38 Expression Good or Bad? https://www.mdpi.com/2073-4409/9/2/378

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #146

                                        pdf
                                        https://sci-hub.tw/https://www.mdpi.com/2073-4409/9/2/378

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #147

                                          part of Special Issue "CD38 and Disease: A Bi-Directional Cross-Talk between Pathology and Physiology" https://www.mdpi.com/journal/cells/special_issues/CD38_CD157

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