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Genmab — November 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • Helge_LarsenPI-redaktørH Offline
    Helge_LarsenPI-redaktørH Offline
    Helge_LarsenPI-redaktør
    wrote on sidst redigeret af
    #721

    Just a moment...

    favicon

    (www.proinvestor.com)

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    0
    • Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktør
      wrote on sidst redigeret af
      #722

      Godnat fra Regstrup med denne fra Mette. https://www.proinvestor.com/debat/78899#postdiv78992

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      0
      • Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktør
        wrote on sidst redigeret af
        #723

        Tak Mette. 🙂

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        • D Offline
          D Offline
          DevOp
          wrote on sidst redigeret af
          #724

          Tak for link Bulder. Det må så være Large B cell lymphoma og AML, der tænkes på i første omgang som nye targets for Hexa-Dara. Og det er da noget af en forøgelse af effekten i MM, endda også for en Dara refraktær. Men spændende, at de også ser effekt i 17 ud af 28 tumor cell lines, som ikke påvirkes af Dara.

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #725

            Successful Treatment of Refractory Red Cell Aplasia after Allogeneic Hematopoietic Cell Transplantation with Daratumumab https://onlinelibrary.wiley.com/doi/abs/10.1111/ejh.13343 full article http://sci-hub.tw/https://onlinelibrary.wiley.com/doi/abs/10.1111/ejh.13343#.XcVzedlJAbA.twitter

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #726

              http://sci-hub.tw/https://onlinelibrary.wiley.com/doi/abs/10.1111/ejh.13343#.XcVzedlJAbA.twitter

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #727

                Ofatumumab rescue treatment in post-transplant recurrence of focal segmental glomerulosclerosis https://link.springer.com/article/10.1007/s00467-019-04365-w full art http://sci-hub.tw/https://link.springer.com/article/10.1007/s00467-019-04365-w

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #728

                  http://sci-hub.tw/https://link.springer.com/article/10.1007/s00467-019-04365-w

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                  • P Offline
                    P Offline
                    peter12
                    wrote on sidst redigeret af
                    #729

                    Findes der andre "hexabody" platforme derude ?

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #730

                      GEN1029 =
                      HexaBody-DR5/DR5

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #731

                        DuoHexabody-CD37 = 2019 IND/CTA target, still expect this to go into the clinic before the end of the year

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #732

                          repeating a link from yesterday; the CD123 x CD3 DuoBody increased Enrollment from 60 to 120 (which gives me some new hope on this trial) https://clinicaltrials.gov/ct2/history/NCT02715011?A=28&B=29&C=merged#StudyPageTop

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                          • P Offline
                            P Offline
                            peter12
                            wrote on sidst redigeret af
                            #733

                            n
                            on-Genmab hexabodies platforms ?

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                            0
                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #734

                              peter12: Der forskes i hvert fald i det andre steder, men om andre firmaer har en decideret hexamerizations-platform ved jeg ikke. Måske Sukkeralf? https://www.ncbi.nlm.nih.gov/pubmed/28578024

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                              • P Offline
                                P Offline
                                peter12
                                wrote on sidst redigeret af
                                #735

                                Det er nok et guldæg de har der.

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #736

                                  Genmab currently only has commercial partners for the DuoBody technology, Janssen, BioNTech, Novo
                                  Nordisk, and Gilead Sciences. But we are all eagerly awaiting new deals 😉

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                                  • Helge_LarsenPI-redaktørH Offline
                                    Helge_LarsenPI-redaktørH Offline
                                    Helge_LarsenPI-redaktør
                                    wrote on sidst redigeret af
                                    #737

                                    Just a moment...

                                    favicon

                                    (www.proinvestor.com)

                                    1 Reply Last reply
                                    0
                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #738

                                      Vi fik i går at vide at IMS' salgstal (39mio$ gns pr uge i oktober) er bruttotal før rabatter. SH's tal ligger ca 14% over JnJ's. Hvis vi antager det samme for IMS får vi nettosalg på 33,5mio$ pr uge i oktober. Hvis us ikke stiger yderligere i nov og dec skal row stige 18% fra q3 til q4.

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #739

                                        kkjoel regnede forleden med 13 uger for okt, nov, dec. Jeg har kun regnet med 12 pga juleugen.

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                                        0
                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #740

                                          Såååh, jeg tror ikke det bliver ret meget over 3 mia$

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                                          0

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