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Genmab — November 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • J Offline
    J Offline
    JKY_VH
    wrote on sidst redigeret af
    #718

    Jeg har længe haft samme tanke Solsen

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    0
    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #719

      abstractet, Winkel henviser til, når han skriver: " HexaBody CD38 can effectively kill tumors that are not sensitive to Daratumumab. https://ash.confex.com/ash/2019/webprogram/Paper125788.html

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #720

        https://twitter.com/BertrandBio/status/1192901954013401089

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        0
        • Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktør
          wrote on sidst redigeret af
          #721

          Just a moment...

          favicon

          (www.proinvestor.com)

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          0
          • Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktør
            wrote on sidst redigeret af
            #722

            Godnat fra Regstrup med denne fra Mette. https://www.proinvestor.com/debat/78899#postdiv78992

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            0
            • Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktør
              wrote on sidst redigeret af
              #723

              Tak Mette. 🙂

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              • D Offline
                D Offline
                DevOp
                wrote on sidst redigeret af
                #724

                Tak for link Bulder. Det må så være Large B cell lymphoma og AML, der tænkes på i første omgang som nye targets for Hexa-Dara. Og det er da noget af en forøgelse af effekten i MM, endda også for en Dara refraktær. Men spændende, at de også ser effekt i 17 ud af 28 tumor cell lines, som ikke påvirkes af Dara.

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #725

                  Successful Treatment of Refractory Red Cell Aplasia after Allogeneic Hematopoietic Cell Transplantation with Daratumumab https://onlinelibrary.wiley.com/doi/abs/10.1111/ejh.13343 full article http://sci-hub.tw/https://onlinelibrary.wiley.com/doi/abs/10.1111/ejh.13343#.XcVzedlJAbA.twitter

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #726

                    http://sci-hub.tw/https://onlinelibrary.wiley.com/doi/abs/10.1111/ejh.13343#.XcVzedlJAbA.twitter

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #727

                      Ofatumumab rescue treatment in post-transplant recurrence of focal segmental glomerulosclerosis https://link.springer.com/article/10.1007/s00467-019-04365-w full art http://sci-hub.tw/https://link.springer.com/article/10.1007/s00467-019-04365-w

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #728

                        http://sci-hub.tw/https://link.springer.com/article/10.1007/s00467-019-04365-w

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                        • P Offline
                          P Offline
                          peter12
                          wrote on sidst redigeret af
                          #729

                          Findes der andre "hexabody" platforme derude ?

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                          0
                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #730

                            GEN1029 =
                            HexaBody-DR5/DR5

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                            0
                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #731

                              DuoHexabody-CD37 = 2019 IND/CTA target, still expect this to go into the clinic before the end of the year

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                              0
                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #732

                                repeating a link from yesterday; the CD123 x CD3 DuoBody increased Enrollment from 60 to 120 (which gives me some new hope on this trial) https://clinicaltrials.gov/ct2/history/NCT02715011?A=28&B=29&C=merged#StudyPageTop

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                                • P Offline
                                  P Offline
                                  peter12
                                  wrote on sidst redigeret af
                                  #733

                                  n
                                  on-Genmab hexabodies platforms ?

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                                  0
                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #734

                                    peter12: Der forskes i hvert fald i det andre steder, men om andre firmaer har en decideret hexamerizations-platform ved jeg ikke. Måske Sukkeralf? https://www.ncbi.nlm.nih.gov/pubmed/28578024

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                                    • P Offline
                                      P Offline
                                      peter12
                                      wrote on sidst redigeret af
                                      #735

                                      Det er nok et guldæg de har der.

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                                      0
                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #736

                                        Genmab currently only has commercial partners for the DuoBody technology, Janssen, BioNTech, Novo
                                        Nordisk, and Gilead Sciences. But we are all eagerly awaiting new deals 😉

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                                        0
                                        • Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktør
                                          wrote on sidst redigeret af
                                          #737

                                          https://www.proinvestor.com/index.php?p=debat_1&postid=79003

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