Genmab — November 2019

[E_L]

it works for me, in Chrome and Internet Explorer ?

[E_L]

timing wise it would makes sense as BioNtech and Aduro/BioNovion both partnered with Genmab in 2015? if i am not mistaken...

[E_L]

so given recent trials with BioNtech I mean, could be time for Aduro

[E_L]

“The achievement of starting a Phase I/IIa clinical trial with a product candidate developed in only four years is a validation of our highly productive partnership with Genmab,” said Prof. Ugur Sahin, CEO of BioNTech - RE timing

[Sukkeralf]

Aduro and Genmab has terminated their collaboration

[E_L]

o really? i missed that...

[Bulder]

Sukker, hvad mener du om den bispecifikke car-t - bcma x cd38. Jacob Plieth nævner den ikke. Men Usmani er begejstret. https://ash.confex.com/ash/2019/webprogram/Paper130340.html

[Sukkeralf]

This collaboration was
terminated in the fourth quarter of 2018.

[Sukkeralf]

Page 41

[Sukkeralf]

https://ir.genmab.com/static-files/2d42acad-9313-4900-9e0e-12c6cf16f10d

[E_L]

ok , thks, the paper may have started before, it reads "Financial support for this work was obtained
from Aduro Biotech Europe and Genmab." Given that the Genmab authors get "Acknowledgments" it may be Aduro that now runs with it?

[GeorgeBest]

flot stigning i dag. specielt når der tages i betragtning at der blev exercised warrants i går aftes. der bliver nok hæftig aktivitet i lukkeauktionen...

[Sukkeralf]

E L - you are probably right

[Sukkeralf]

Bulder har ikke set på den endnu

[Sukkeralf]

Bulder data ser meget stærke ud, men altid svært med CAR-T - uden at kende meget til området som sådan, så lyder det umiddelbart endnu mere kompliceret, så svært at vurdere potentialet salgsmæssigt !

[Bulder]

Men det virker "oplagt" at lave en cd38x bcma netop i MM. Sjovt at ingen har fundet på netop den "kombi" for en almindelig bispecifik.

[Sukkeralf]

måske endnu bedre med Janssens BCMA-CD3 i kombi med daratumumab

[Bulder]

... eller den forstærkede hex-cd38

[Legolas23]

Jeg mener JDW er spurgt om hex-cd38?

[Sukkeralf]

Alligevel også lidt svært at forestille sig hvis ikke Janssen har kigget på dara som bispecific - måske grunden til at de kun delvist er sprunget med på hex-CD38. Det kan være der er et bispecifict CD38 antistof i rugekassen