Genmab — November 2019
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Ofatumumab rescue treatment in post-transplant recurrence of focal segmental glomerulosclerosis https://link.springer.com/article/10.1007/s00467-019-04365-w full art http://sci-hub.tw/https://link.springer.com/article/10.1007/s00467-019-04365-w
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repeating a link from yesterday; the CD123 x CD3 DuoBody increased Enrollment from 60 to 120 (which gives me some new hope on this trial) https://clinicaltrials.gov/ct2/history/NCT02715011?A=28&B=29&C=merged#StudyPageTop
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peter12: Der forskes i hvert fald i det andre steder, men om andre firmaer har en decideret hexamerizations-platform ved jeg ikke. Måske Sukkeralf? https://www.ncbi.nlm.nih.gov/pubmed/28578024
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Vi fik i går at vide at IMS' salgstal (39mio$ gns pr uge i oktober) er bruttotal før rabatter. SH's tal ligger ca 14% over JnJ's. Hvis vi antager det samme for IMS får vi nettosalg på 33,5mio$ pr uge i oktober. Hvis us ikke stiger yderligere i nov og dec skal row stige 18% fra q3 til q4.
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Jeg mener David nævnte at italien var kommet med på dara for nylig ? Så lige at Velcade kan fås generisk fra Q2 https://pharmaintelligence.informa.com/~/media/informa-shop-window/pharma/2019/files/infographic/market_acces_phase2_infographic.pdf
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Peter12 der findes i hvert fald mange teknologier/platforme til at forbedre effector functions - og synes altid Genmab har haft særlig meget fokus på CDC. Kigger man i nedenstående link tabel 8, så lader det til at dannelse af hexamere er relativ nyt:
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