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Genmab — November 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • Helge_LarsenPI-redaktørH Offline
    Helge_LarsenPI-redaktørH Offline
    Helge_LarsenPI-redaktør
    wrote on sidst redigeret af
    #722

    Godnat fra Regstrup med denne fra Mette. https://www.proinvestor.com/debat/78899#postdiv78992

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    0
    • Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktør
      wrote on sidst redigeret af
      #723

      Tak Mette. 🙂

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      0
      • D Offline
        D Offline
        DevOp
        wrote on sidst redigeret af
        #724

        Tak for link Bulder. Det må så være Large B cell lymphoma og AML, der tænkes på i første omgang som nye targets for Hexa-Dara. Og det er da noget af en forøgelse af effekten i MM, endda også for en Dara refraktær. Men spændende, at de også ser effekt i 17 ud af 28 tumor cell lines, som ikke påvirkes af Dara.

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #725

          Successful Treatment of Refractory Red Cell Aplasia after Allogeneic Hematopoietic Cell Transplantation with Daratumumab https://onlinelibrary.wiley.com/doi/abs/10.1111/ejh.13343 full article http://sci-hub.tw/https://onlinelibrary.wiley.com/doi/abs/10.1111/ejh.13343#.XcVzedlJAbA.twitter

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #726

            http://sci-hub.tw/https://onlinelibrary.wiley.com/doi/abs/10.1111/ejh.13343#.XcVzedlJAbA.twitter

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #727

              Ofatumumab rescue treatment in post-transplant recurrence of focal segmental glomerulosclerosis https://link.springer.com/article/10.1007/s00467-019-04365-w full art http://sci-hub.tw/https://link.springer.com/article/10.1007/s00467-019-04365-w

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #728

                http://sci-hub.tw/https://link.springer.com/article/10.1007/s00467-019-04365-w

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                • P Offline
                  P Offline
                  peter12
                  wrote on sidst redigeret af
                  #729

                  Findes der andre "hexabody" platforme derude ?

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #730

                    GEN1029 =
                    HexaBody-DR5/DR5

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #731

                      DuoHexabody-CD37 = 2019 IND/CTA target, still expect this to go into the clinic before the end of the year

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #732

                        repeating a link from yesterday; the CD123 x CD3 DuoBody increased Enrollment from 60 to 120 (which gives me some new hope on this trial) https://clinicaltrials.gov/ct2/history/NCT02715011?A=28&B=29&C=merged#StudyPageTop

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                        • P Offline
                          P Offline
                          peter12
                          wrote on sidst redigeret af
                          #733

                          n
                          on-Genmab hexabodies platforms ?

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                          0
                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #734

                            peter12: Der forskes i hvert fald i det andre steder, men om andre firmaer har en decideret hexamerizations-platform ved jeg ikke. Måske Sukkeralf? https://www.ncbi.nlm.nih.gov/pubmed/28578024

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                            • P Offline
                              P Offline
                              peter12
                              wrote on sidst redigeret af
                              #735

                              Det er nok et guldæg de har der.

                              1 Reply Last reply
                              0
                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #736

                                Genmab currently only has commercial partners for the DuoBody technology, Janssen, BioNTech, Novo
                                Nordisk, and Gilead Sciences. But we are all eagerly awaiting new deals 😉

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                                • Helge_LarsenPI-redaktørH Offline
                                  Helge_LarsenPI-redaktørH Offline
                                  Helge_LarsenPI-redaktør
                                  wrote on sidst redigeret af
                                  #737

                                  Just a moment...

                                  favicon

                                  (www.proinvestor.com)

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                                  0
                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #738

                                    Vi fik i går at vide at IMS' salgstal (39mio$ gns pr uge i oktober) er bruttotal før rabatter. SH's tal ligger ca 14% over JnJ's. Hvis vi antager det samme for IMS får vi nettosalg på 33,5mio$ pr uge i oktober. Hvis us ikke stiger yderligere i nov og dec skal row stige 18% fra q3 til q4.

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #739

                                      kkjoel regnede forleden med 13 uger for okt, nov, dec. Jeg har kun regnet med 12 pga juleugen.

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #740

                                        Såååh, jeg tror ikke det bliver ret meget over 3 mia$

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                                        0
                                        • Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktør
                                          wrote on sidst redigeret af
                                          #741

                                          Just a moment...

                                          favicon

                                          (www.proinvestor.com)

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                                          0

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