Genmab — November 2019
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abstractet, Winkel henviser til, når han skriver: " HexaBody CD38 can effectively kill tumors that are not sensitive to Daratumumab. https://ash.confex.com/ash/2019/webprogram/Paper125788.html
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Godnat fra Regstrup med denne fra Mette. https://www.proinvestor.com/debat/78899#postdiv78992
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Tak Mette.
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Tak for link Bulder. Det må så være Large B cell lymphoma og AML, der tænkes på i første omgang som nye targets for Hexa-Dara. Og det er da noget af en forøgelse af effekten i MM, endda også for en Dara refraktær. Men spændende, at de også ser effekt i 17 ud af 28 tumor cell lines, som ikke påvirkes af Dara.
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Successful Treatment of Refractory Red Cell Aplasia after Allogeneic Hematopoietic Cell Transplantation with Daratumumab https://onlinelibrary.wiley.com/doi/abs/10.1111/ejh.13343 full article http://sci-hub.tw/https://onlinelibrary.wiley.com/doi/abs/10.1111/ejh.13343#.XcVzedlJAbA.twitter
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Ofatumumab rescue treatment in post-transplant recurrence of focal segmental glomerulosclerosis https://link.springer.com/article/10.1007/s00467-019-04365-w full art http://sci-hub.tw/https://link.springer.com/article/10.1007/s00467-019-04365-w
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repeating a link from yesterday; the CD123 x CD3 DuoBody increased Enrollment from 60 to 120 (which gives me some new hope on this trial) https://clinicaltrials.gov/ct2/history/NCT02715011?A=28&B=29&C=merged#StudyPageTop
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peter12: Der forskes i hvert fald i det andre steder, men om andre firmaer har en decideret hexamerizations-platform ved jeg ikke. Måske Sukkeralf? https://www.ncbi.nlm.nih.gov/pubmed/28578024
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Vi fik i går at vide at IMS' salgstal (39mio$ gns pr uge i oktober) er bruttotal før rabatter. SH's tal ligger ca 14% over JnJ's. Hvis vi antager det samme for IMS får vi nettosalg på 33,5mio$ pr uge i oktober. Hvis us ikke stiger yderligere i nov og dec skal row stige 18% fra q3 til q4.
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