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Genmab — September 2019

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #722

    yes, that made me revisit this. here is the SEC form F1 https://sec.report/Document/0001140361-19-016305/

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #723

      it contains a short explanation of ADCT-301 and also : Key elements of our strategy are outlined below:

      • .
      • Advance our second lead product candidate, ADCT-301, to support BLA submission in the first half of 2022.

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #724

        and then i also thought "Risks Related to Our Relationship with Third Parties" was interesting as it says "Our rights to ADCT-301 are subject to our collaboration and license agreement with Genmab, and there can be no assurance that we will maintain the rights to develop or commercialize ADCT-301."

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #725

          Our collaboration and license agreement with Genmab requires a divestment of ADCT-301, in which Genmab has a 25% interest, following database lock for the Phase 1/2 clinical trial. The agreement sets out a defined process to facilitate the divestment of ADCT-301 by licensing the rights thereto to a third party, subject to Genmab’s right of first opportunity to negotiate to acquire ADCT-301 in full.

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #726

            p148 is also interesting

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #727

              the Lundbeck Parkinson's trial a bit delayed, doesn't seem to recruit very enthusiastically https://clinicaltrials.gov/ct2/history/NCT03611569?A=2&B=3&C=merged#StudyPageTop

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              • StockBullS Offline
                StockBullS Offline
                StockBull
                wrote on sidst redigeret af
                #728

                Kursen søger ned mod styrkeområdet 1360-80. Tror der ligger den del s.l i det område.Vi må håbe de 1360 holder.

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                • A Offline
                  A Offline
                  AaBforever
                  wrote on sidst redigeret af
                  #729

                  Lad os få good news så den kan søge opad igen..:-)

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                  • K Offline
                    K Offline
                    kkjoel
                    wrote on sidst redigeret af
                    #730

                    Ja, yderst interessant EL. Har GEN virkelig stadig muligheden fo
                    r at "genovertage" ADCT-301.....??

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                    • K Offline
                      K Offline
                      kkjoel
                      wrote on sidst redigeret af
                      #731

                      Her fortsættelsen af det sidste afsnit, EL citerede: "
                      This process includes the opportunity for both parties to bid for the license rights alongside third parties. Both parties are required to use commercially reasonable efforts to complete and maximize the value obtained in this process. Therefore, our rights to ADCT-301 are subject to our collaboration and license agreement with Genmab, and there can be no assurance that we will apply for regulatory approval of or commercialize ADCT-301."

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                      • K Offline
                        K Offline
                        kkjoel
                        wrote on sidst redigeret af
                        #732

                        Kan fx Sukker, Bulder, Solsen eller EL kaste lidt lys over disse formuleringer og forhold?

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #733

                          Tja, jeg forstår det også sådan at Genmab kan erhverve (eller i hvert fald byde på) de udestående 75%, når fase 1/2 studiet er færdigt.

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #734

                            Så det bliver nok engang i løbet af 2021, at data er klar, så de kan vurdere om de vil kaste (flere) penge efter stoffet.

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #735

                              Horizon Therapeutics plc Announces the FDA has Granted Priority Review of the Teprotumumab Biologics License Application (BLA) for the Treatment of Active Thyroid Eye Disease (TED) https://www.businesswire.com/news/home/20190909005532/en/Horizon-Therapeutics-plc-Announces-FDA-Granted-Priority/?feedref=JjAwJuNHiystnCoBq_hl-W8j9Oi60kFTomUxRDB8jhBsNpnJw7dvSfTyni2BOVIOrCOi9QzgjCezTS3Nw_X6kJUrpSBm-Hav1w-UkdSlG3nDlC87j5HoE75BMeA8LaVacVjEfZIyqgxRRsuxHCTK2w%3D%3D&utm_source=dlvr.it&utm_medium=twitter

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #736

                                (PDUFA) goal date is March 8, 2020

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                                • K Offline
                                  K Offline
                                  kkjoel
                                  wrote on sidst redigeret af
                                  #737

                                  Genmab and Tempus Enter into Strategic Collaboration Agreement

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                                  • K Offline
                                    K Offline
                                    kkjoel
                                    wrote on sidst redigeret af
                                    #738

                                    https://ir.genmab.com/news-releases/news-release-details/genmab-and-tempus-enter-strategic-collaboration-agreement

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                                    • K Offline
                                      K Offline
                                      kkjoel
                                      wrote on sidst redigeret af
                                      #739

                                      Genmab A/S (Nasdaq: GMAB) announced today that it has entered into a strategic collaboration agreement with Tempus, a privately-owned technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.

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                                      • K Offline
                                        K Offline
                                        kkjoel
                                        wrote on sidst redigeret af
                                        #740

                                        The multi-year collaboration will combine Tempus’ sequencing capabilities and industry-leading platform of integrated clinical and molecular data with Genmab’s state-of-the-art translational, biomarker and target discovery expertise. The companies will work together, based upon novel insights identified by Genmab, to advance new disease targets and biomarkers that may have the potential to generate new treatments in oncology.

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                                        • K Offline
                                          K Offline
                                          kkjoel
                                          wrote on sidst redigeret af
                                          #741

                                          This new strategic collaboration builds upon existing service agreements between the companies. Under the terms of the collaboration agreement, the companies will jointly work on research projects that are identified by Genmab to explore novel product concepts and biomarkers.

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