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Genmab — September 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • S Offline
    S Offline
    Sukkeralf
    wrote on sidst redigeret af
    #721

    ADC Therapeutics IPO:

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #722

      yes, that made me revisit this. here is the SEC form F1 https://sec.report/Document/0001140361-19-016305/

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #723

        it contains a short explanation of ADCT-301 and also : Key elements of our strategy are outlined below:

        • .
        • Advance our second lead product candidate, ADCT-301, to support BLA submission in the first half of 2022.

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #724

          and then i also thought "Risks Related to Our Relationship with Third Parties" was interesting as it says "Our rights to ADCT-301 are subject to our collaboration and license agreement with Genmab, and there can be no assurance that we will maintain the rights to develop or commercialize ADCT-301."

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #725

            Our collaboration and license agreement with Genmab requires a divestment of ADCT-301, in which Genmab has a 25% interest, following database lock for the Phase 1/2 clinical trial. The agreement sets out a defined process to facilitate the divestment of ADCT-301 by licensing the rights thereto to a third party, subject to Genmab’s right of first opportunity to negotiate to acquire ADCT-301 in full.

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #726

              p148 is also interesting

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #727

                the Lundbeck Parkinson's trial a bit delayed, doesn't seem to recruit very enthusiastically https://clinicaltrials.gov/ct2/history/NCT03611569?A=2&B=3&C=merged#StudyPageTop

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                • StockBullS Offline
                  StockBullS Offline
                  StockBull
                  wrote on sidst redigeret af
                  #728

                  Kursen søger ned mod styrkeområdet 1360-80. Tror der ligger den del s.l i det område.Vi må håbe de 1360 holder.

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                  • A Offline
                    A Offline
                    AaBforever
                    wrote on sidst redigeret af
                    #729

                    Lad os få good news så den kan søge opad igen..:-)

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                    • K Offline
                      K Offline
                      kkjoel
                      wrote on sidst redigeret af
                      #730

                      Ja, yderst interessant EL. Har GEN virkelig stadig muligheden fo
                      r at "genovertage" ADCT-301.....??

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                      • K Offline
                        K Offline
                        kkjoel
                        wrote on sidst redigeret af
                        #731

                        Her fortsættelsen af det sidste afsnit, EL citerede: "
                        This process includes the opportunity for both parties to bid for the license rights alongside third parties. Both parties are required to use commercially reasonable efforts to complete and maximize the value obtained in this process. Therefore, our rights to ADCT-301 are subject to our collaboration and license agreement with Genmab, and there can be no assurance that we will apply for regulatory approval of or commercialize ADCT-301."

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                        • K Offline
                          K Offline
                          kkjoel
                          wrote on sidst redigeret af
                          #732

                          Kan fx Sukker, Bulder, Solsen eller EL kaste lidt lys over disse formuleringer og forhold?

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #733

                            Tja, jeg forstår det også sådan at Genmab kan erhverve (eller i hvert fald byde på) de udestående 75%, når fase 1/2 studiet er færdigt.

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #734

                              Så det bliver nok engang i løbet af 2021, at data er klar, så de kan vurdere om de vil kaste (flere) penge efter stoffet.

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #735

                                Horizon Therapeutics plc Announces the FDA has Granted Priority Review of the Teprotumumab Biologics License Application (BLA) for the Treatment of Active Thyroid Eye Disease (TED) https://www.businesswire.com/news/home/20190909005532/en/Horizon-Therapeutics-plc-Announces-FDA-Granted-Priority/?feedref=JjAwJuNHiystnCoBq_hl-W8j9Oi60kFTomUxRDB8jhBsNpnJw7dvSfTyni2BOVIOrCOi9QzgjCezTS3Nw_X6kJUrpSBm-Hav1w-UkdSlG3nDlC87j5HoE75BMeA8LaVacVjEfZIyqgxRRsuxHCTK2w%3D%3D&utm_source=dlvr.it&utm_medium=twitter

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #736

                                  (PDUFA) goal date is March 8, 2020

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                                  • K Offline
                                    K Offline
                                    kkjoel
                                    wrote on sidst redigeret af
                                    #737

                                    Genmab and Tempus Enter into Strategic Collaboration Agreement

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                                    • K Offline
                                      K Offline
                                      kkjoel
                                      wrote on sidst redigeret af
                                      #738

                                      https://ir.genmab.com/news-releases/news-release-details/genmab-and-tempus-enter-strategic-collaboration-agreement

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                                      • K Offline
                                        K Offline
                                        kkjoel
                                        wrote on sidst redigeret af
                                        #739

                                        Genmab A/S (Nasdaq: GMAB) announced today that it has entered into a strategic collaboration agreement with Tempus, a privately-owned technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.

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                                        • K Offline
                                          K Offline
                                          kkjoel
                                          wrote on sidst redigeret af
                                          #740

                                          The multi-year collaboration will combine Tempus’ sequencing capabilities and industry-leading platform of integrated clinical and molecular data with Genmab’s state-of-the-art translational, biomarker and target discovery expertise. The companies will work together, based upon novel insights identified by Genmab, to advance new disease targets and biomarkers that may have the potential to generate new treatments in oncology.

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