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Genmab — September 2019

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #719

    not sure if this new trial was posted already : Study to Evaluate the Efficacy and Safety of Camidanlumab Tesirine (ADCT-301) in Patients With Relapsed or Refractory Hodgkin Lymphoma https://clinicaltrials.gov/ct2/show/NCT04052997?term=Camidanlumab&rank=1

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    • S Offline
      S Offline
      Sukkeralf
      wrote on sidst redigeret af
      #720

      Just a moment...

      favicon

      (www.firstwordpharma.com)

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      • S Offline
        S Offline
        Sukkeralf
        wrote on sidst redigeret af
        #721

        ADC Therapeutics IPO:

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #722

          yes, that made me revisit this. here is the SEC form F1 https://sec.report/Document/0001140361-19-016305/

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #723

            it contains a short explanation of ADCT-301 and also : Key elements of our strategy are outlined below:

            • .
            • Advance our second lead product candidate, ADCT-301, to support BLA submission in the first half of 2022.

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #724

              and then i also thought "Risks Related to Our Relationship with Third Parties" was interesting as it says "Our rights to ADCT-301 are subject to our collaboration and license agreement with Genmab, and there can be no assurance that we will maintain the rights to develop or commercialize ADCT-301."

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #725

                Our collaboration and license agreement with Genmab requires a divestment of ADCT-301, in which Genmab has a 25% interest, following database lock for the Phase 1/2 clinical trial. The agreement sets out a defined process to facilitate the divestment of ADCT-301 by licensing the rights thereto to a third party, subject to Genmab’s right of first opportunity to negotiate to acquire ADCT-301 in full.

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #726

                  p148 is also interesting

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #727

                    the Lundbeck Parkinson's trial a bit delayed, doesn't seem to recruit very enthusiastically https://clinicaltrials.gov/ct2/history/NCT03611569?A=2&B=3&C=merged#StudyPageTop

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                    • StockBullS Offline
                      StockBullS Offline
                      StockBull
                      wrote on sidst redigeret af
                      #728

                      Kursen søger ned mod styrkeområdet 1360-80. Tror der ligger den del s.l i det område.Vi må håbe de 1360 holder.

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                      • A Offline
                        A Offline
                        AaBforever
                        wrote on sidst redigeret af
                        #729

                        Lad os få good news så den kan søge opad igen..:-)

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                        • K Offline
                          K Offline
                          kkjoel
                          wrote on sidst redigeret af
                          #730

                          Ja, yderst interessant EL. Har GEN virkelig stadig muligheden fo
                          r at "genovertage" ADCT-301.....??

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                          • K Offline
                            K Offline
                            kkjoel
                            wrote on sidst redigeret af
                            #731

                            Her fortsættelsen af det sidste afsnit, EL citerede: "
                            This process includes the opportunity for both parties to bid for the license rights alongside third parties. Both parties are required to use commercially reasonable efforts to complete and maximize the value obtained in this process. Therefore, our rights to ADCT-301 are subject to our collaboration and license agreement with Genmab, and there can be no assurance that we will apply for regulatory approval of or commercialize ADCT-301."

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                            • K Offline
                              K Offline
                              kkjoel
                              wrote on sidst redigeret af
                              #732

                              Kan fx Sukker, Bulder, Solsen eller EL kaste lidt lys over disse formuleringer og forhold?

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #733

                                Tja, jeg forstår det også sådan at Genmab kan erhverve (eller i hvert fald byde på) de udestående 75%, når fase 1/2 studiet er færdigt.

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #734

                                  Så det bliver nok engang i løbet af 2021, at data er klar, så de kan vurdere om de vil kaste (flere) penge efter stoffet.

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #735

                                    Horizon Therapeutics plc Announces the FDA has Granted Priority Review of the Teprotumumab Biologics License Application (BLA) for the Treatment of Active Thyroid Eye Disease (TED) https://www.businesswire.com/news/home/20190909005532/en/Horizon-Therapeutics-plc-Announces-FDA-Granted-Priority/?feedref=JjAwJuNHiystnCoBq_hl-W8j9Oi60kFTomUxRDB8jhBsNpnJw7dvSfTyni2BOVIOrCOi9QzgjCezTS3Nw_X6kJUrpSBm-Hav1w-UkdSlG3nDlC87j5HoE75BMeA8LaVacVjEfZIyqgxRRsuxHCTK2w%3D%3D&utm_source=dlvr.it&utm_medium=twitter

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #736

                                      (PDUFA) goal date is March 8, 2020

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                                      • K Offline
                                        K Offline
                                        kkjoel
                                        wrote on sidst redigeret af
                                        #737

                                        Genmab and Tempus Enter into Strategic Collaboration Agreement

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                                        • K Offline
                                          K Offline
                                          kkjoel
                                          wrote on sidst redigeret af
                                          #738

                                          https://ir.genmab.com/news-releases/news-release-details/genmab-and-tempus-enter-strategic-collaboration-agreement

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