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Genmab — September 2019

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • T Offline
    T Offline
    transalp
    wrote on sidst redigeret af
    #716

    Go morgen.. 🙂

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    • B Offline
      B Offline
      bibob
      wrote on sidst redigeret af
      #717

      God morgen fra syden. 🙂

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      • B Offline
        B Offline
        bibob
        wrote on sidst redigeret af
        #718

        Ser ikke ud til det store rebound idag.

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #719

          not sure if this new trial was posted already : Study to Evaluate the Efficacy and Safety of Camidanlumab Tesirine (ADCT-301) in Patients With Relapsed or Refractory Hodgkin Lymphoma https://clinicaltrials.gov/ct2/show/NCT04052997?term=Camidanlumab&rank=1

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          • S Offline
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            Sukkeralf
            wrote on sidst redigeret af
            #720

            Just a moment...

            favicon

            (www.firstwordpharma.com)

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            • S Offline
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              Sukkeralf
              wrote on sidst redigeret af
              #721

              ADC Therapeutics IPO:

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              • E Offline
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                E_L
                wrote on sidst redigeret af
                #722

                yes, that made me revisit this. here is the SEC form F1 https://sec.report/Document/0001140361-19-016305/

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #723

                  it contains a short explanation of ADCT-301 and also : Key elements of our strategy are outlined below:

                  • .
                  • Advance our second lead product candidate, ADCT-301, to support BLA submission in the first half of 2022.

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #724

                    and then i also thought "Risks Related to Our Relationship with Third Parties" was interesting as it says "Our rights to ADCT-301 are subject to our collaboration and license agreement with Genmab, and there can be no assurance that we will maintain the rights to develop or commercialize ADCT-301."

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                    • E Offline
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                      E_L
                      wrote on sidst redigeret af
                      #725

                      Our collaboration and license agreement with Genmab requires a divestment of ADCT-301, in which Genmab has a 25% interest, following database lock for the Phase 1/2 clinical trial. The agreement sets out a defined process to facilitate the divestment of ADCT-301 by licensing the rights thereto to a third party, subject to Genmab’s right of first opportunity to negotiate to acquire ADCT-301 in full.

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                      • E Offline
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                        E_L
                        wrote on sidst redigeret af
                        #726

                        p148 is also interesting

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #727

                          the Lundbeck Parkinson's trial a bit delayed, doesn't seem to recruit very enthusiastically https://clinicaltrials.gov/ct2/history/NCT03611569?A=2&B=3&C=merged#StudyPageTop

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                          • StockBullS Offline
                            StockBullS Offline
                            StockBull
                            wrote on sidst redigeret af
                            #728

                            Kursen søger ned mod styrkeområdet 1360-80. Tror der ligger den del s.l i det område.Vi må håbe de 1360 holder.

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                            • A Offline
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                              AaBforever
                              wrote on sidst redigeret af
                              #729

                              Lad os få good news så den kan søge opad igen..:-)

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                              • K Offline
                                K Offline
                                kkjoel
                                wrote on sidst redigeret af
                                #730

                                Ja, yderst interessant EL. Har GEN virkelig stadig muligheden fo
                                r at "genovertage" ADCT-301.....??

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                                • K Offline
                                  K Offline
                                  kkjoel
                                  wrote on sidst redigeret af
                                  #731

                                  Her fortsættelsen af det sidste afsnit, EL citerede: "
                                  This process includes the opportunity for both parties to bid for the license rights alongside third parties. Both parties are required to use commercially reasonable efforts to complete and maximize the value obtained in this process. Therefore, our rights to ADCT-301 are subject to our collaboration and license agreement with Genmab, and there can be no assurance that we will apply for regulatory approval of or commercialize ADCT-301."

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                                  • K Offline
                                    K Offline
                                    kkjoel
                                    wrote on sidst redigeret af
                                    #732

                                    Kan fx Sukker, Bulder, Solsen eller EL kaste lidt lys over disse formuleringer og forhold?

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #733

                                      Tja, jeg forstår det også sådan at Genmab kan erhverve (eller i hvert fald byde på) de udestående 75%, når fase 1/2 studiet er færdigt.

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #734

                                        Så det bliver nok engang i løbet af 2021, at data er klar, så de kan vurdere om de vil kaste (flere) penge efter stoffet.

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                                        • E Offline
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                                          E_L
                                          wrote on sidst redigeret af
                                          #735

                                          Horizon Therapeutics plc Announces the FDA has Granted Priority Review of the Teprotumumab Biologics License Application (BLA) for the Treatment of Active Thyroid Eye Disease (TED) https://www.businesswire.com/news/home/20190909005532/en/Horizon-Therapeutics-plc-Announces-FDA-Granted-Priority/?feedref=JjAwJuNHiystnCoBq_hl-W8j9Oi60kFTomUxRDB8jhBsNpnJw7dvSfTyni2BOVIOrCOi9QzgjCezTS3Nw_X6kJUrpSBm-Hav1w-UkdSlG3nDlC87j5HoE75BMeA8LaVacVjEfZIyqgxRRsuxHCTK2w%3D%3D&utm_source=dlvr.it&utm_medium=twitter

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