Genmab — September 2019
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Bowers oplyser, at han ikke er bekendt med andre stoffer i fase 3 der har ligget under 0,15 i ARR. Ofa havde 0;10-0,11 og var i patienter der var senere i MS forløbet end i Ocrevus forsøgene hhv 8,2 og 6,7 år efter diagnose og derfor sværere patienter at behandle. Ergo “best in class” med førnævnte forbehold.
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Enig.
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I er sgu søde - farvede - men søde
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du er berettiget til dine egne meninger - men ikke dine egne facts
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Vi nåede over en 1/2 mia...hold da op!
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Patients on ofatumumab had a relapse rate of 0.1. That’s a single relapse every 10 years, which is quite unheard of,” Bar-Zohar said. “When we looked at the inflammatory rate in the brain with MRI, ofatumumab showed highly significant, almost complete suppression of disease activity as compared to Aubagio
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Ofatumumab binds to its target in such a way that allows for a relatively low dose of the drug to be used, so if patients need to go off the drug—say to treat an infection—their B cell population recovers quickly, he said: “The recovery takes about half the time as it does with the infused drugs
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