Genmab — August 2019
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Børsstop.
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Om DLBCL,FL,MCL studiet:The study also experienced a high screen failure rate, where only 63 (56%) of 112 screened patients with available tumor samples had CD38 expression ≥ 50% across all 3 NHL cohorts. Among these patients with CD38 expression ≥ 50%, only 36 were eligible for study enrollment, questioning the generalizability of the study population.
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targeting CD38 may still have potential as a treatment for NHL subtypes in different patient populations or by using different anti-CD38 treatment strategies.36 A threshold for CD38 expression remains to be defined, and the role of synergistic activity in combination with other therapies, such as rituximab, CHOP, or lenalidomide
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