Genmab — August 2019

[Bulder]

In none of the studies dara is a combo-partner. Only opponent in dreamm 7. Could be a compo partner in dreamm 10 though.

[Sukkeralf]

Yes a bit strange Bulder - Jan has mentioned several times that the BCMA target could be combined with daratumumab. And looking at daratumumabs position its very strange that they dont partner up

[Bulder]

Maybe they await Janssen to come up with and finance a study.

[Sukkeralf]

A wild spekulation could be that Janssen dont wat to give them sc dosing of dara because they would combine it with either their CAR-T BCMA or CD3/BCMA. And GSK will not use IV dosing because it will be old fashion in a couple of years

[Sukkeralf]

So until sc dosing is approved GSK must wait

[bibob]

Sounds right Sukker.

[E_L]

we need a GSK Q&A @Helge

[Helge_LarsenPI-redaktør]

[bibob]

Yes E L. And a chat about good Wine and food when we have got good news on a friday with Big raise for Genmab.

[JKY_VH]

[Bulder]

Den chat har vi da allerede. Der bliver ikke snakket om andet.

[bibob]

Bulder. Den burde bare have sin egen da den jo fylder så meget.

[E_L]

[Bulder]

så er den gal på Nordnet igen. Skifter konstant mellem realtid og 15 min forsinket.

[gentogen]

Om DLBCL,FL,MCL studiet:The study also experienced a high screen failure rate, where only 63 (56%) of 112 screened patients with available tumor samples had CD38 expression ≥ 50% across all 3 NHL cohorts. Among these patients with CD38 expression ≥ 50%, only 36 were eligible for study enrollment, questioning the generalizability of the study population.

[gentogen]

targeting CD38 may still have potential as a treatment for NHL subtypes in different patient populations or by using different anti-CD38 treatment strategies.36 A threshold for CD38 expression remains to be defined, and the role of synergistic activity in combination with other therapies, such as rituximab, CHOP, or lenalidomide

[gentogen]

Clinical Lymphoma Myeloma and Leukemia
Volume 19, Issue 5, May 2019, Pages 275-284

[Nike]

Spændende at se hvor godt GEN står fast i når Kina-told-stormen manglende rente-nedsættelse

[OHW]

Kina har lige meddelt, at de øger tolden på amerikanske vare. Samtidig frygtes voldsom aktiekursfald, hvis FED chefen her klokken 16 oplyser, at der ikke komme flere rentesænkninger.

[Bulder]

Når han nu ikke kunne få Grønland, hvorfor køber han så ikke Kina?