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Genmab — Juni 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • nohopeN Offline
    nohopeN Offline
    nohope
    wrote on sidst redigeret af
    #629

    I´ll welcome almost any kind of deals, also, this deal, but it does seem rather far away from what Jan has been talking about. This is a techdeal with a product, this should have been paid upfront and/or on 50/50 basis. But any hole in the no-deal-wall is welcome to me.

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #630

      I am actually very excited about this deal- Dara is the backbone of this company and Genmab is looking to strengthen and extend that backbone. Extremely important and a sign of mature management with a long term view imo. I really like Sukkeralf's term 'life cycle management' in this respect.

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #631

        @nohope 09:21 is my answer to that.

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        • nohopeN Offline
          nohopeN Offline
          nohope
          wrote on sidst redigeret af
          #632

          Well, you could also say, this emphasasi that GEN is a one-trick pony - Darapony.

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #633

            even if that would be right; i would rather have a strong pony that lives longer 😉

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            • nohopeN Offline
              nohopeN Offline
              nohope
              wrote on sidst redigeret af
              #634

              Ok, I see. Too bad, but still better than the Theresa May scenario 😉

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              • nohopeN Offline
                nohopeN Offline
                nohope
                wrote on sidst redigeret af
                #635

                Ponies forever 😉

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                • SolsenS Offline
                  SolsenS Offline
                  Solsen
                  wrote on sidst redigeret af
                  #636

                  To me the agreement is still like Genmab asking Janssens for a deal - not a move from Janssens.

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                  • SolsenS Offline
                    SolsenS Offline
                    Solsen
                    wrote on sidst redigeret af
                    #637

                    Perhaps its foresight ?

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                    • S Offline
                      S Offline
                      Sukkeralf
                      wrote on sidst redigeret af
                      #638

                      when sc dosing of CD38 it should be secured until 2033-35...........a with all the alternatives Janssen is doing right now I agree with Solsen that Genmab has pushed this foreward and Janssen at last agree to "show us what it can do"

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                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #639

                        But a nice deal to get in place before a DR5/DR5 deal and to get HexaBody and perhaps HexElect in the spotlight

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                        • troldmandenT Offline
                          troldmandenT Offline
                          troldmanden
                          wrote on sidst redigeret af
                          #640

                          mindes ikke lige at have set en sådan struktureret deal før. Uden noget i upfront

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                          • troldmandenT Offline
                            troldmandenT Offline
                            troldmanden
                            wrote on sidst redigeret af
                            #641

                            POC kan være defineret lidt forskelligt. Men cost bør ikke opverstige 200 mio, og det over de næste 3-4 år. Så det beløb betyder i sig selv ikke noget for genmab. De har også sagt det ikke ændre på forventningerne

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                            • troldmandenT Offline
                              troldmandenT Offline
                              troldmanden
                              wrote on sidst redigeret af
                              #642

                              det er gratis for jansen at lave denne aftale, og de sikre sig endda at Genmab ikke må sætte den op som direkte konkurrent til dara, såfremt jannsen skulle undlade at udnytte optionen

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                              • troldmandenT Offline
                                troldmandenT Offline
                                troldmanden
                                wrote on sidst redigeret af
                                #643

                                Should Janssen not exercise its option, the terms of the agreement allow Genmab to continue to develop and commercialize HexaBody-CD38 for DARZALEX-resistant patients, and in all other indications except those multiple myeloma or amyloidosis indications where DARZALEX is either approved or is being actively developed.

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                                • G Offline
                                  G Offline
                                  gentogen
                                  wrote on sidst redigeret af
                                  #644

                                  Ja, men det er vel en OK pointe, at de i givet fald gerne må i Dara-resistente. Det er svært at forestille sig JNJ ikke slå til, hvis det er bedre end Dara...

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                                  • S Offline
                                    S Offline
                                    Sukkeralf
                                    wrote on sidst redigeret af
                                    #645

                                    Troldmanden det er jo også en ret usædvanlig situation - man kan vel næppe finde en lignende. Janssen har meget i gang mod MM og Genmab kan ikke gøre dette uden Janssens tilladelse (eller det virker nok formålsløst, da de ikke kan komme i mål), så vel en meget naturlig måde aftalen er skruet sammen på.

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                                    • S Offline
                                      S Offline
                                      Sukkeralf
                                      wrote on sidst redigeret af
                                      #646

                                      Vis os det virker så skal vi nok slå til - de skal vel bringe det nogenlunde lige så langt frem (nok en tand længere) en daratumumab var - og så slår Janssen til på nogenlunde samme termer (mindre milestone og bedre royalty).

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                                      • StockBullS Offline
                                        StockBullS Offline
                                        StockBull
                                        wrote on sidst redigeret af
                                        #647

                                        Hvor lang til mon der går inden JNJ udnytter optionen hvis det kommer dertil ?

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                                        • S Offline
                                          S Offline
                                          Sukkeralf
                                          wrote on sidst redigeret af
                                          #648

                                          Der må ligge noget veldefineret, for ellers giver det ingen mening.

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