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Genmab — Marts 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #541

    Creating Lasting Benefit With CAR T-Cell Therapy in Myeloma
    https://www.onclive.com/web-exclusives/creating-lasting-benefit-with-car-tcell-therapy-in-myeloma?p=1

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    • Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktør
      wrote on sidst redigeret af
      #542

      God morgen. 🙂

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      • P Offline
        P Offline
        polle1
        wrote on sidst redigeret af
        #543

        God morgen og god dag 🙂

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        • T Offline
          T Offline
          transalp
          wrote on sidst redigeret af
          #544

          Go morgen derude.. 🙂

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          • Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktør
            wrote on sidst redigeret af
            #545

            https://play.borsen.dk/social/5c8643b3595ab4f00a32ff35

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #546

              JNJ has announced that (NICE) has recommended Darzalex® (daratumumab) plus Velcade® (bortezomib) and dexamethasone (DVd) for use within the Cancer Drugs Fund (CDF), as an option for treating relapsed multiple myeloma in people who have had one previous treatment. https://pharmafield.co.uk/pharma_news/nice-nod-for-game-changing-treatment-via-cdf-for-uk-myeloma-patients/

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #547

                on NICE https://www.nice.org.uk/guidance/indevelopment/gid-ta10174/documents

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #548

                  Cancer Research UK : ‘Game-changing’ myeloma drug combo approved for NHS use in England ‘Game-changing’ myeloma drug combo approved for NHS use in England

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #549

                    https://www.cancerresearchuk.org/about-us/cancer-news/news-report/2019-03-12-game-changing-myeloma-drug-combo-approved-for-nhs-use-in-england

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                    • T Offline
                      T Offline
                      Tandfeen-2
                      wrote on sidst redigeret af
                      #550

                      Endelig med nice

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                      • P Offline
                        P Offline
                        peter12
                        wrote on sidst redigeret af
                        #551

                        I 4. linie regnede de med ca 700 pts https://pharmaphorum.com/news/nice-backs-interim-funding-janssen-cancer-drug/

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #552

                          we are not there yet @Tandfeen-2 , still not 1st line and still via CDF, so far from ideal. But it is another step that will increase sales.

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #553

                            "NICE however said that the overall-survival data was ‘immature’ because more than half of the patients treated with the daratumumab combination were alive after nearly four years of follow up." this sounds like, if patients would have died quicker, it would have been easier to approve… crazy...

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                            • P Offline
                              P Offline
                              peter12
                              wrote on sidst redigeret af
                              #554

                              Interesting discussion between Janssen and Nice last year
                              . Dara could reset MM treatment https://www.nice.org.uk/guidance/ta510/documents/committee-papers-2

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                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #555

                                E L I guess that comment is because NICE mainly base their reimbursement on OS data

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #556

                                  yes, i guess you are correct, that is what they base their cost effectiveness study on, but it feels weird to say that it is difficult to measure because they live too long... Anyway, another small step..
                                  .

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #557

                                    What does this mean? They recommend the treatment, but will not reimburse it?

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #558

                                      NHS will not directly fund it, it will be reimbursed out of the Cancer Drugs Fund (CDF), just like currently is the case with mono

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                                      • P Offline
                                        P Offline
                                        peter12
                                        wrote on sidst redigeret af
                                        #559

                                        Genmab var shortet 4,04% 28 feb. Det har ligget på 3-4% det sidste år. Det er positioner over 0,2%

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                                        • J Offline
                                          J Offline
                                          Joakim_Von_And
                                          wrote on sidst redigeret af
                                          #560

                                          Ja,, kunne der komme et bud , så de hurtigt ville i 0 ,, det ville glæde mig at de brændte nallerne lidt...

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