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Genmab — Januar 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • K Offline
    K Offline
    kkjoel
    wrote on sidst redigeret af
    #966

    Have you got any thoughts on response rates on a late 6. line? (It was probably discussed here after ASH.) And any insights into correlation between possibility for "deep" response and how far down treament-regime one is? (maybe also that was discussed here after ASH..)

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    • K Offline
      K Offline
      kkjoel
      wrote on sidst redigeret af
      #967

      Ahhhh, ADCT-601 binder til AXL.. så osse derfor specifkt interessant i GEN regi (enapotamab vedotin)

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      • K Offline
        K Offline
        kkjoel
        wrote on sidst redigeret af
        #968

        Så eftersom begge stoffer binder til AXL, ligner det derfor spørgsmålet om det er ADCTs eller GENs cellegift der er den bedste/kan fåes til at virke bedst?

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        • K Offline
          K Offline
          kkjoel
          wrote on sidst redigeret af
          #969

          Hvor ADCT har deres egen gift, mens GENs kommer fra Seatlle Genetics.

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          • D Offline
            D Offline
            dohk
            wrote on sidst redigeret af
            #970

            Linker teknologien er rigtig vigtig. Linkeren kløves når ADCen transporteres ind i cellen og giften frigives. Der har været problemer med bivirkninger fordi linkeren kløves for tidligt...husker i hvert fald at immunogen havde problemer. SGEN har masser af validering af deres teknologi, så nok derfor Genmab kigger mod dem.

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            • D Offline
              D Offline
              dohk
              wrote on sidst redigeret af
              #971

              Kan ikke huske hvilken linker teknologi ADC technology bruger og hvilken grad af validering den har.

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #972

                Perseus (D-VRd SC) recruiting. Wonder how many of us will still be around here at the end of this trial... 😉 https://clinicaltrials.gov/ct2/history/NCT03710603?A=1&B=2&C=merged

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #973

                  @kkjoel it is still early days for 301... we'll have to wait for a bit more data me thinks

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #974

                    @ E L: I think they'll ask for approval of D-VRd asct based on Griffin, when we get the full data set (and data is good enough). Perseus is just to confirm data, and FDA will probably only give an approval on the condition that they make a large phase 3.

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #975

                      sounds good to me...

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                      0
                      • B Offline
                        B Offline
                        bibob
                        wrote on sidst redigeret af
                        #976

                        Hold da op.!!- shorterne har fået presset Oddset på dansk sejr over Norge ned til 1,58 . 😄

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                        • P Offline
                          P Offline
                          Peter_Panik
                          wrote on sidst redigeret af
                          #977

                          Link Preview Image
                          Siden findes ikke

                          favicon

                          (borsen.dk)

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                          0
                          • P Offline
                            P Offline
                            peter12
                            wrote on sidst redigeret af
                            #978

                            Og det var så noget der skete i oktober. Børsen har vist ikke læst hvad der står ...

                            1 Reply Last reply
                            0
                            • Helge_LarsenPI-redaktørH Offline
                              Helge_LarsenPI-redaktørH Offline
                              Helge_LarsenPI-redaktør
                              wrote on sidst redigeret af
                              #979

                              Genmab Shareholders: Register your email to receive electronic shareholder communications from Genmab incl. the calling to Genmab’s Annual General Meetings. Log on to the InvestorPortal & add your email under “My Profile”. The portal can be accessed from http://www.genmab.com .

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                              • P Offline
                                P Offline
                                Peter_Panik
                                wrote on sidst redigeret af
                                #980

                                Jo, de er hurtige på Børsen. Nyheden tjekkede lige ind som Breaking News på min telefon også. Absurd!

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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #981

                                  Finansielle instrumenter med stemmeret ?

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                                  0
                                  • P Offline
                                    P Offline
                                    peter12
                                    wrote on sidst redigeret af
                                    #982

                                    De troede nok at de havde stemmeret og udbytterefusion på de
                                    lånte aktier 😉

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                                    • P Offline
                                      P Offline
                                      peter12
                                      wrote on sidst redigeret af
                                      #983

                                      udbytteskat refusion, skulle der stå

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                                      0
                                      • P Offline
                                        P Offline
                                        peter12
                                        wrote on sidst redigeret af
                                        #984

                                        Det var vist noget vrøvl - sorry 😉

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                                        0
                                        • L Offline
                                          L Offline
                                          lahn1
                                          wrote on sidst redigeret af
                                          #985

                                          God aften ! Jeg er blevet lidt lyn på verastem i dette prisleje, og vil høre om der er nogle af herinde som har en mening om aktien. Hvad regnede vi med at ofa have af top salg estimat i cll/sll. Tænker at dette spg rammer bedre i GEN chatten end i biotek chatten.

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