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Genmab — December 2018

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • P Offline
    P Offline
    Plimsoller
    wrote on sidst redigeret af
    #103

    Er der overraskelser - positive/negative?

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #104

      KCRD does not look bad https://twitter.com/theMMRF/status/1069260099263188994

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      • G Offline
        G Offline
        GeorgeBest
        wrote on sidst redigeret af
        #105

        dara plus IRd impressive https://twitter.com/ninashah33/status/1069267606647885824?s=21

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        • nohopeN Offline
          nohopeN Offline
          nohope
          wrote on sidst redigeret af
          #106

          Should KCRD be a worry for Dara ?

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          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #107

            Ser man på omkostninger og effektivitet kan dara+CyBorD blive vigtigt. Lyra. https://www.youtube.com/watch?v=z6vkzZYUJfM

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            • G Offline
              G Offline
              GeorgeBest
              wrote on sidst redigeret af
              #108

              CyBorD plus dara MRD- ca. 80% https://twitter.com/michaelodwyermd/status/1069278701676720128?s=21

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              • G Offline
                G Offline
                GeorgeBest
                wrote on sidst redigeret af
                #109

                Det må vel betegnes som overordentlig positivt:-)

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #110

                  Griffin havde 100% VGPR eller bedre. Men er også noget dyrere - formentligt.

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #111

                    Ingen tvivl om at D-VRd vil blive brugt i USA og D+cybord andre steder.

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #112

                      in Syros press release SY-1425 Induced CD38 Expression in Majority of Patients in Daratumumab Combination Cohort in Relapsed/Refractory AML and Higher-Risk MDS Patients https://www.businesswire.com/news/home/20181202005039/en/Syros-Announces-Promising-Clinical-Data-Ongoing-Phase 2

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                      • G Offline
                        G Offline
                        GeorgeBest
                        wrote on sidst redigeret af
                        #113

                        https://twitter.com/northtxmsg/status/1069291379908468736?s=21

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #114

                          JNJ poster states ±`+´

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #115

                            over 52,000 patients treated https://twitter.com/NorthTxMSG/status/1069281456092925952

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                            • G Offline
                              G Offline
                              GeorgeBest
                              wrote on sidst redigeret af
                              #116

                              Centaurus https://twitter.com/mtmdphd/status/1069294708126609410?s=21

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                              • G Offline
                                G Offline
                                GeorgeBest
                                wrote on sidst redigeret af
                                #117

                                Link Preview Image
                                Webprogram Unavailable

                                favicon

                                (ash.confex.com)

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                                • G Offline
                                  G Offline
                                  GeorgeBest
                                  wrote on sidst redigeret af
                                  #118

                                  Vores ven Vincent Ra...https://twitter.com/vincentrk/status/1069262798931148800?s=21

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                                  • T Offline
                                    T Offline
                                    Tandfeen-2
                                    wrote on sidst redigeret af
                                    #119

                                    Skal vi være bange for en kombo uden Dara? Fx KCRD? Nogen, der kender til den

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #120

                                      Andre muligheder er også triplerne KRd og VRd. Dara bliver testet som kvadruplet i begge kombinationer. Og så bliver spørgsmålet om dara gør det så meget bedre, at det er pengene værd. Nu så vi med Maia at dara fordobler effektiviteten ift Rd. Om det er pengene værd vil vise sig. Rajkumars hovedtanke - cost-effectiveness - er relevant i de fleste sammenhænge.

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #121

                                        Konkret om KCRd tror(!) jeg D-KRd bliver bedre. Men prisen?

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                                        • SolsenS Offline
                                          SolsenS Offline
                                          Solsen
                                          wrote on sidst redigeret af
                                          #122

                                          Hamdeksbanken tror der står dara på de næste 3-4 år. CAR-T frygten er væk for en stund. Men ADC og Bispecifik er stigende frygt. De henviser til en afstemning, hvor Ventoclax har øget interesse.

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