Genmab — December 2018
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Den tør man ikke tænke på....
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Er der overraskelser - positive/negative?
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KCRD does not look bad https://twitter.com/theMMRF/status/1069260099263188994
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dara plus IRd impressive https://twitter.com/ninashah33/status/1069267606647885824?s=21
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Ser man på omkostninger og effektivitet kan dara+CyBorD blive vigtigt. Lyra. https://www.youtube.com/watch?v=z6vkzZYUJfM
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CyBorD plus dara MRD- ca. 80% https://twitter.com/michaelodwyermd/status/1069278701676720128?s=21
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Det må vel betegnes som overordentlig positivt:-)
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in Syros press release
SY-1425 Induced CD38 Expression in Majority of Patients in Daratumumab Combination Cohort in Relapsed/Refractory AML and Higher-Risk MDS Patientshttps://www.businesswire.com/news/home/20181202005039/en/Syros-Announces-Promising-Clinical-Data-Ongoing-Phase 2 -
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over 52,000 patients treated https://twitter.com/NorthTxMSG/status/1069281456092925952
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Vores ven Vincent Ra...https://twitter.com/vincentrk/status/1069262798931148800?s=21
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Skal vi være bange for en kombo uden Dara? Fx KCRD? Nogen, der kender til den
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Andre muligheder er også triplerne KRd og VRd. Dara bliver testet som kvadruplet i begge kombinationer. Og så bliver spørgsmålet om dara gør det så meget bedre, at det er pengene værd. Nu så vi med Maia at dara fordobler effektiviteten ift Rd. Om det er pengene værd vil vise sig. Rajkumars hovedtanke - cost-effectiveness - er relevant i de fleste sammenhænge.
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