Genmab — November 2018

[E_L]

@gentogen 1 of the forum members a while ago mentioned ATRA being rather toxic if i am correct, can't remember who it was

[E_L]

@peter12 P5 and P6 seem to indicate we can expect a new trial based on this? "The results of these
analyses have led to the approval of a phase-II
clinical study that will be testing Dara in
relapsed/refractory CLL patients."

[Bulder]

There is only one phase 1 study in cll running as far as I can see. So it looks like a new one to come. Nice that dara is being tested in different leukemias.

[E_L]

yes, good news

[Bulder]

The two Duobodies, Peter mentions, are the two presented at CMD recently. There will be INDs H1 next year.

[E_L]

GEN1042 = DuoBody-CD40x4-1BB was mentioned by Genmab in January as a 2018 IND candidate

[Bulder]

Yes but according to CMD it's been delayed it seems.

[E_L]

yes, i am just seeing it, both to H1 2019

[E_L]

to many to remember all lol

[E_L]

nice proof that it is moving forward, with these abstracts ; good find @peter12

[Bulder]

excellent find

[peter12]

We better put an eye on our socks

[E_L]

ADCT-301 (Cami-T) is also on 2 posters, P11 and P316

[gentogen]

Ang. 16:03. Fra andet studie: "The toxicity profile was mild and reversible. No secondary carcinoma was observed, and 24 months after the last dose of ATRA/ATO, patients had urine arsenic concentrations well below the safety limit. These results demonstrate the high efficacy and minimal toxicity of ATRA/ATO treatment for newly diagnosed APL in long-term follow-up"

[E_L]

ok, that seems fine, thanks

[JKY_VH]

Rart at se Nordea som største nettokøber. Mon Novod har tilgivet JVW ?

[bibob]

Han kunne jo starte med at hæve target med 500 kurspoint.

[JKY_VH]

ja, men det varer desværre nok lidt:-)

[bibob]

Han kan da også bare vente det halve år til vi er der alligevel . så kan han smide 500 mere i.

[JKY_VH]

haha, god strategi;-)