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Genmab — November 2018

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #164

    Pollux: 51,2% CR eller bedre. 26,2% MRDneg i 10 i minus 5. Vi skal være opmærksomme på hvilken tærskel, der anvendes i MRD. https://www.ncbi.nlm.nih.gov/pubmed/30237262

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    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #165

      Der er fandens til forskel på 10 i minus 4. og 6.

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #166

        abstracts via https://ash.confex.com/ash/2018/webprogram/start.html

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #167

          156One-Year Update of a Phase 3 Randomized Study of Daratumumab Plus Bortezomib, Melphalan, and Prednisone (D-VMP) Versus Bortezomib, Melphalan, and Prednisone (VMP) in Patients (Pts) with Transplant-Ineligible Newly Diagnosed Multiple Myeloma (NDMM): Alcyone https://ash.confex.com/ash/2018/webprogram/Paper113183.html

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #168

            After median follow-up of 27.8 months, median PFS was NR for D-VMP vs 19.1 months for VMP

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #169

              trying to figure out which ones are most important, too many to post all here...

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #170

                Griffin https://ash.confex.com/ash/2018/webprogram/Paper113122.html

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #171

                  100% vgpr or better. så kører det

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #172

                    Genmabs release, a bit easier to find the important ones https://ir.genmab.com/news-releases/news-release-details/genmab-announces-data-be-presented-2018-ash-annual-meeting

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                    • SolsenS Offline
                      SolsenS Offline
                      Solsen
                      wrote on sidst redigeret af
                      #173

                      Thirty-five total abstracts on Genmab owned and partnered programs scheduled for presentation at ASH
                      •Three abstracts related to Genmab owned programs: DuoBody®-CD3xCD20 & DuoHexaBody™-CD37
                      •Daratumumab: 5 oral presentations; total of 30 accepted including ISS

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                      • SolsenS Offline
                        SolsenS Offline
                        Solsen
                        wrote on sidst redigeret af
                        #174

                        Imponerende !!!

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #175

                          sure is, Jan will be proud

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #176

                            To prove the anti-leukemic activity of daratumumab in AML in vivo https://ash.confex.com/ash/2018/webprogram/Paper113287.html

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                            • StockBullS Offline
                              StockBullS Offline
                              StockBull
                              wrote on sidst redigeret af
                              #177

                              Firework and champagne

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                              • B Offline
                                B Offline
                                bibob
                                wrote on sidst redigeret af
                                #178

                                Sagde han ikke også at de ville komme til at dominere ASH

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #179

                                  Lyra er med som oral!

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                                  • StockBullS Offline
                                    StockBullS Offline
                                    StockBull
                                    wrote on sidst redigeret af
                                    #180

                                    dominere i antal ser det ud til - forhåbentlig også i kvalitet af data 🙂

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #181

                                      Conclusions: CyBorD-DARA is a highly active, well tolerated induction therapy for NDMM patients undergoing ASCT. https://ash.confex.com/ash/2018/webprogram/Paper112375.html

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                                      • B Offline
                                        B Offline
                                        bibob
                                        wrote on sidst redigeret af
                                        #182

                                        Vel ingen grund til at præsentere hvis data er dårlige 😉

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #183

                                          Conclusions:
                                          CyBorD-DARA is a highly active, well tolerated induction therapy for NDMM patients undergoing ASCT. https://ash.confex.com/ash/2018/webprogram/Paper112375.html

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