Genmab — November 2018
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Det vil jeg umiddelbart tro, Bulder
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Pollux: 51,2% CR eller bedre. 26,2% MRDneg i 10 i minus 5. Vi skal være opmærksomme på hvilken tærskel, der anvendes i MRD. https://www.ncbi.nlm.nih.gov/pubmed/30237262
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abstracts via https://ash.confex.com/ash/2018/webprogram/start.html
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156One-Year Update of a Phase 3 Randomized Study of Daratumumab Plus Bortezomib, Melphalan, and Prednisone (D-VMP) Versus Bortezomib, Melphalan, and Prednisone (VMP) in Patients (Pts) with Transplant-Ineligible Newly Diagnosed Multiple Myeloma (NDMM): Alcyone https://ash.confex.com/ash/2018/webprogram/Paper113183.html
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Genmabs release, a bit easier to find the important ones https://ir.genmab.com/news-releases/news-release-details/genmab-announces-data-be-presented-2018-ash-annual-meeting
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Thirty-five total abstracts on Genmab owned and partnered programs scheduled for presentation at ASH
•Three abstracts related to Genmab owned programs: DuoBody
-CD3xCD20 & DuoHexaBody
-CD37
•Daratumumab: 5 oral presentations; total of 30 accepted including ISS -
To prove the anti-leukemic activity of daratumumab in AML in vivo https://ash.confex.com/ash/2018/webprogram/Paper113287.html
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Conclusions: CyBorD-DARA is a highly active, well tolerated induction therapy for NDMM patients undergoing ASCT. https://ash.confex.com/ash/2018/webprogram/Paper112375.html
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