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Genmab — Maj 2018

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • P Offline
    P Offline
    pauly
    wrote on sidst redigeret af
    #609

    Lukken bliver interessant, mere end sædvanligt

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    • G Offline
      G Offline
      gentogen
      wrote on sidst redigeret af
      #610

      Safety and efficacy of daratumumab in combination with bortezomib and dexamethasone in Japanese patients with relapsed or refractory multiple myeloma. Lille studie, men 100% ORR. https://link.springer.com/article/10.1007/s12185-017-2390-2

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      • G Offline
        G Offline
        gentogen
        wrote on sidst redigeret af
        #611

        Blood Cancer Journal (maj 2018):Daratumumab, lenalidomide, and dexamethasone in East Asian patients with relapsed or refractory multiple myeloma: subgroup analyses of the phase 3 POLLUX study

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        • G Offline
          G Offline
          gentogen
          wrote on sidst redigeret af
          #612

          the addition of daratumumab to Rd led to prolonged PFS with increased and deeper responses compared with Rd alone in both East Asian patients and Japanese patients from POLLUX, consistent with findings in the international POLLUX population. Given the recent approval of daratumumab in combination with lenalidomide and dexamethasone as a new treatment option in Japan13, these findings suggest that this regimen is a new standard of care for Japanese patients with RRMM

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          • Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktør
            wrote on sidst redigeret af
            #613

            Tak gentogen. Jans optimisme med Japan er velbegrundet.

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            • Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktør
              wrote on sidst redigeret af
              #614

              Q&A starter om 5 minutter.

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              0
              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #615

                Winkel talte om nogle små sikkerhedsstudier, der skulle være færdige og medsendes Alcyone, inden de kunne ansøge om godkendelse i Japan.

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                • J Offline
                  J Offline
                  jkj
                  wrote on sidst redigeret af
                  #616

                  Mange gode spørgsmål, og lidt for mange politiker svar.

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                  0
                  • Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktør
                    wrote on sidst redigeret af
                    #617

                    Tusinde tak for mange gode og skarpe spørgsmål til alle. 🙂

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                    0
                    • M Offline
                      M Offline
                      mobbyduck1
                      wrote on sidst redigeret af
                      #618

                      @jkj, lige mine tanker

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                      0
                      • Legolas23L Offline
                        Legolas23L Offline
                        Legolas23
                        wrote on sidst redigeret af
                        #619

                        Han trak jnj kortet mange gange

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                        0
                        • Legolas23L Offline
                          Legolas23L Offline
                          Legolas23
                          wrote on sidst redigeret af
                          #620

                          men fine svar vedr Duobody

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                          0
                          • Helge_LarsenPI-redaktørH Offline
                            Helge_LarsenPI-redaktørH Offline
                            Helge_LarsenPI-redaktør
                            wrote on sidst redigeret af
                            #621

                            Netop. Det var meget positivt.

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                            0
                            • Legolas23L Offline
                              Legolas23L Offline
                              Legolas23
                              wrote on sidst redigeret af
                              #622

                              Han lovede nyt i 18 fra Duo

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                              0
                              • Helge_LarsenPI-redaktørH Offline
                                Helge_LarsenPI-redaktørH Offline
                                Helge_LarsenPI-redaktør
                                wrote on sidst redigeret af
                                #623

                                Jeps.

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                                0
                                • Legolas23L Offline
                                  Legolas23L Offline
                                  Legolas23
                                  wrote on sidst redigeret af
                                  #624

                                  "we very much look forward to further progress with products created with the DuoBody technology..."

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                                  0
                                  • Legolas23L Offline
                                    Legolas23L Offline
                                    Legolas23
                                    wrote on sidst redigeret af
                                    #625

                                    the CD3 arm and the antibody has been 'silenced' in a unique manner......on top of this, we are using the DuoBody in patients in an entirely new way. So lots to test in a clinical setting.

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #626

                                      Til gengæld kan vi vist godt lukke ned for reaktoren - jeg tænker på actinium-225.

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                                      • Legolas23L Offline
                                        Legolas23L Offline
                                        Legolas23
                                        wrote on sidst redigeret af
                                        #627

                                        Kunne du tolke, hvad han mente med "the antibody has been 'silenced' in a unique manner..." ?

                                        1 Reply Last reply
                                        0
                                        • Legolas23L Offline
                                          Legolas23L Offline
                                          Legolas23
                                          wrote on sidst redigeret af
                                          #628

                                          Hentyder han til safety ?

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                                          0

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