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Genmab — November 2017

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • O Offline
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    OHW
    wrote on sidst redigeret af
    #63

    Investigator initiated studies (IIS) are clinical studies initiated and managed by a non-pharmaceutical company researchers, like individual investigators, institutions, collaborative study groups or cooperative groups. The researcher is responsible for the legal and regulatory responsibilities of the trial sponsor for the conduct and management of the study as defined by all applicable laws and regulations.

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    • M Offline
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      Mcjean
      wrote on sidst redigeret af
      #64

      Da du skriver at den blev snakket op, en kæmpe selvmodsigelse:-), men jeg forstår hvad du mener

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      • M Offline
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        Mcjean
        wrote on sidst redigeret af
        #65

        Abstract 739 viser at Drd er markant bedre end dr og .......This updated analysis reveals that DRd continues to demonstrate a significant PFS benefit compared with Rd alone, and pt responses continue to deepen with DRd with longer follow up. Pts who receive DRd demonstrated longer time to next therapy and responded more favorably to subsequent therapy as evidenced by prolonged PFS2, suggesting that patients continue to observe clinical benefit from prior daratumumab treatment. Importantly, the

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        • M Offline
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          Mcjean
          wrote on sidst redigeret af
          #66

          favorable safety profile was maintained with longer follow-up. These data support the addition of daratumumab to standard of care regimens in RRMM.

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          • V Offline
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            Vitus
            wrote on sidst redigeret af
            #67

            Den KUNNE snakkes op.... den tid er forbi -:)

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            • J Offline
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              Jedi
              wrote on sidst redigeret af
              #68

              Synes ikke jeg kan se Alcyone blandt abstract highlights fra Genmab - kommer den mon på som late-breaking abstract i stedet for?

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              • G Offline
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                gentogen
                wrote on sidst redigeret af
                #69

                Studies on how Dara and the ID combination induce direct programmed cell death (independent of modulating BCR signaling) are underway. Overall, our investigations provide rationale for clinical testing of Ibr combined with Dara in CLL

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                  gentogen
                  wrote on sidst redigeret af
                  #70

                  ibr = Ibrutinib

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                    gentogen
                    wrote on sidst redigeret af
                    #71

                    With further preclinical results supporting these data, to be shared at the conference, our investigations provide rationale for clinical testing of Ibr + Dara in WM

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                    • M Offline
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                      Mcjean
                      wrote on sidst redigeret af
                      #72

                      Abstract 739: scr 26% vs 9% - vgpr 79% vs 48% taler deres eget tydelige sprog.

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                      • J Offline
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                        Jedi
                        wrote on sidst redigeret af
                        #73

                        Abstract 510 Smoldering (Centaurus) ORR 56% i den arm med bedst performance, men kun 1 pt med CR

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                        • M Offline
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                          Mcjean
                          wrote on sidst redigeret af
                          #74

                          Abstract 838 ser da ud til at bivirkningsprofilen er markant lavere ved sc end uden.

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                            Sukkeralf
                            wrote on sidst redigeret af
                            #75

                            overskriften er fin.

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                              Sukkeralf
                              wrote on sidst redigeret af
                              #76

                              Link Preview Image
                              Webprogram Unavailable

                              favicon

                              (ash.confex.com)

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                                Mcjean
                                wrote on sidst redigeret af
                                #77

                                Gentogen er det abstract 3019 du omtaler?

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                                • M Offline
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                                  Mcjean
                                  wrote on sidst redigeret af
                                  #78

                                  Nogen af eksperterne, der har en kommentar til denne? https://ash.confex.com/ash/2017/webprogram/Paper104702.html

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                                    Mogan
                                    wrote on sidst redigeret af
                                    #79

                                    Markedet taler desværre i mere negativ retning. Kræver virkelig tålmodighed og det lange lys på.

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                                    • J Offline
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                                      JohnW
                                      wrote on sidst redigeret af
                                      #80

                                      Jeg synes det fortsatte kursfald er en overdreven reaktion. Er der nogle der ved om den er under angreb af shortere?

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                                        Sukkeralf
                                        wrote on sidst redigeret af
                                        #81

                                        http://ir.genmab.com/releasedetail.cfm?ReleaseID=1046489

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                                          Sukkeralf
                                          wrote on sidst redigeret af
                                          #82

                                          Fra Genmab:

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