Genmab — November 2017

[Mcjean]

Abstract 739 viser at Drd er markant bedre end dr og .......This updated analysis reveals that DRd continues to demonstrate a significant PFS benefit compared with Rd alone, and pt responses continue to deepen with DRd with longer follow up. Pts who receive DRd demonstrated longer time to next therapy and responded more favorably to subsequent therapy as evidenced by prolonged PFS2, suggesting that patients continue to observe clinical benefit from prior daratumumab treatment. Importantly, the

[Mcjean]

favorable safety profile was maintained with longer follow-up. These data support the addition of daratumumab to standard of care regimens in RRMM.

[Vitus]

Den KUNNE snakkes op.... den tid er forbi -:)

[Jedi]

Synes ikke jeg kan se Alcyone blandt abstract highlights fra Genmab - kommer den mon på som late-breaking abstract i stedet for?

[gentogen]

Studies on how Dara and the ID combination induce direct programmed cell death (independent of modulating BCR signaling) are underway. Overall, our investigations provide rationale for clinical testing of Ibr combined with Dara in CLL

[gentogen]

ibr = Ibrutinib

[gentogen]

With further preclinical results supporting these data, to be shared at the conference, our investigations provide rationale for clinical testing of Ibr + Dara in WM

[Mcjean]

Abstract 739: scr 26% vs 9% - vgpr 79% vs 48% taler deres eget tydelige sprog.

[Jedi]

Abstract 510 Smoldering (Centaurus) ORR 56% i den arm med bedst performance, men kun 1 pt med CR

[Mcjean]

Abstract 838 ser da ud til at bivirkningsprofilen er markant lavere ved sc end uden.

[Sukkeralf]

overskriften er fin.

[Sukkeralf]

Webprogram Unavailable

(ash.confex.com)

[Mcjean]

Gentogen er det abstract 3019 du omtaler?

[Mcjean]

Nogen af eksperterne, der har en kommentar til denne? https://ash.confex.com/ash/2017/webprogram/Paper104702.html

[Mogan]

Markedet taler desværre i mere negativ retning. Kræver virkelig tålmodighed og det lange lys på.

[JohnW]

Jeg synes det fortsatte kursfald er en overdreven reaktion. Er der nogle der ved om den er under angreb af shortere?

[Sukkeralf]

http://ir.genmab.com/releasedetail.cfm?ReleaseID=1046489

[Sukkeralf]

Fra Genmab:

[Bulder]

Sukker, kunne det se ud til at bispecifik BCMA x cd3 er mere sikker end car-t BCMA?

[henrik48]

Det var dog en imponerende masse abstracts der bliver lagt frem !!!