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Genmab — Juni 2017

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #1869

    EHA is happening now, started
    yesterday https://www.ehaweb.org/congress-and-events/22nd-congress/program-by-day-2/

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #1870

      Bulder , havent read it completely yet, but we have a BCMA CD3 DuoBody in the clinic, right?

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #1871

        "we" lol

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #1872

          ClinicalTrials.gov

          favicon

          (clinicaltrials.gov)

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          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #1873

            Jo, men interviewet er let forståeligt for os lægfolk. Og giver indblik i hvordan bispecifikke antistoffer virker.

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            • SolsenS Offline
              SolsenS Offline
              Solsen
              wrote on sidst redigeret af
              #1874

              Look forward to se the first duobody data in human !

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              • SolsenS Offline
                SolsenS Offline
                Solsen
                wrote on sidst redigeret af
                #1875

                Does anyone know when that could happen ?

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #1876

                  ASH 2018?

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #1877

                    yes it is Bulder, i saved it for later
                    reading

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #1878

                      Ved nogen om der er planer om at lave en sc-version af JNJ...957?

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                      • G Offline
                        G Offline
                        gentogen
                        wrote on sidst redigeret af
                        #1879

                        Could daratumumab be used to treat severe allergy? I Journal of Allergy and Clinical Immunology. Volume 139, Issue 5, May 2017, Pages 1677–1678.e3.

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                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #1880

                          Jan har flere gange tidlige sagt, at Xencor/Amgens CD38/CD3 ikke er vejen frem og Janssen havde noget bedre i støbeskeen. Da Janssen offentliggjorde deres BCMA/CD3 var Celgene vist uden med riven og sige, at det ikke var vejen frem med et bispecifikt antistof mod dette target - og nu er de selv på vej

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #1881

                            Vi havde temaet oppe i januar http://www.acsh.org/news/2017/01/30/blood-cancer-drug-could-treat-severe-allergies-10792

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                            • G Offline
                              G Offline
                              gentogen
                              wrote on sidst redigeret af
                              #1882

                              Tak

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                              • G Offline
                                G Offline
                                gentogen
                                wrote on sidst redigeret af
                                #1883

                                Enhancement of Anti-Tumor Activities of Daratumumab Using ALT-803, an IL-15 Superagonist, in an Experimental Model and Against Primary Human Lymphoma Cells. The Journal of Immunology
                                Vol. 198, Issue 1 Supplement
                                1 May 2017

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                                • S Offline
                                  S Offline
                                  Sukkeralf
                                  wrote on sidst redigeret af
                                  #1884

                                  Ja det er da lidt interessant - spurgte Jan for lang tid siden om de havde planer om brug af Dara uden for cancer over tid, men der sagde han nej - tror svaret vil være det samme i dag. Vi skal nok håbe på Dara i et ISS. SC dosering vil være endnu mere oplagt, så måske om nogle år

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                                  • SolsenS Offline
                                    SolsenS Offline
                                    Solsen
                                    wrote on sidst redigeret af
                                    #1885

                                    Han blev spurgt af Bowers om netop brug af dara i autoimmune sygdomme - han ville ikke svare på spøgsmålet da JNJ monkeys var til stede. SLE er en oplagt mulighed for dara...

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                                    • B Offline
                                      B Offline
                                      bibob
                                      wrote on sidst redigeret af
                                      #1886

                                      Ved ikke om denne har været vist fra 15/6 https://www.youtube.com/watch?v=fsTrNvN3WYs

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                                      • B Offline
                                        B Offline
                                        bibob
                                        wrote on sidst redigeret af
                                        #1887

                                        Plessner fra 8/6 https://www.youtube.com/watch?v=RaewRYsZHkA

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                                        • Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktør
                                          wrote on sidst redigeret af
                                          #1888

                                          Dejlig video. Tak for den. 🙂

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                                          0

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