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Genmab — Juni 2017

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #1870

    Bulder , havent read it completely yet, but we have a BCMA CD3 DuoBody in the clinic, right?

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #1871

      "we" lol

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #1872

        ClinicalTrials.gov

        favicon

        (clinicaltrials.gov)

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        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #1873

          Jo, men interviewet er let forståeligt for os lægfolk. Og giver indblik i hvordan bispecifikke antistoffer virker.

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          • SolsenS Offline
            SolsenS Offline
            Solsen
            wrote on sidst redigeret af
            #1874

            Look forward to se the first duobody data in human !

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            • SolsenS Offline
              SolsenS Offline
              Solsen
              wrote on sidst redigeret af
              #1875

              Does anyone know when that could happen ?

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              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #1876

                ASH 2018?

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #1877

                  yes it is Bulder, i saved it for later
                  reading

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #1878

                    Ved nogen om der er planer om at lave en sc-version af JNJ...957?

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                    • G Offline
                      G Offline
                      gentogen
                      wrote on sidst redigeret af
                      #1879

                      Could daratumumab be used to treat severe allergy? I Journal of Allergy and Clinical Immunology. Volume 139, Issue 5, May 2017, Pages 1677–1678.e3.

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                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #1880

                        Jan har flere gange tidlige sagt, at Xencor/Amgens CD38/CD3 ikke er vejen frem og Janssen havde noget bedre i støbeskeen. Da Janssen offentliggjorde deres BCMA/CD3 var Celgene vist uden med riven og sige, at det ikke var vejen frem med et bispecifikt antistof mod dette target - og nu er de selv på vej

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #1881

                          Vi havde temaet oppe i januar http://www.acsh.org/news/2017/01/30/blood-cancer-drug-could-treat-severe-allergies-10792

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                          • G Offline
                            G Offline
                            gentogen
                            wrote on sidst redigeret af
                            #1882

                            Tak

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                            • G Offline
                              G Offline
                              gentogen
                              wrote on sidst redigeret af
                              #1883

                              Enhancement of Anti-Tumor Activities of Daratumumab Using ALT-803, an IL-15 Superagonist, in an Experimental Model and Against Primary Human Lymphoma Cells. The Journal of Immunology
                              Vol. 198, Issue 1 Supplement
                              1 May 2017

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                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #1884

                                Ja det er da lidt interessant - spurgte Jan for lang tid siden om de havde planer om brug af Dara uden for cancer over tid, men der sagde han nej - tror svaret vil være det samme i dag. Vi skal nok håbe på Dara i et ISS. SC dosering vil være endnu mere oplagt, så måske om nogle år

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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #1885

                                  Han blev spurgt af Bowers om netop brug af dara i autoimmune sygdomme - han ville ikke svare på spøgsmålet da JNJ monkeys var til stede. SLE er en oplagt mulighed for dara...

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                                  • B Offline
                                    B Offline
                                    bibob
                                    wrote on sidst redigeret af
                                    #1886

                                    Ved ikke om denne har været vist fra 15/6 https://www.youtube.com/watch?v=fsTrNvN3WYs

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                                    • B Offline
                                      B Offline
                                      bibob
                                      wrote on sidst redigeret af
                                      #1887

                                      Plessner fra 8/6 https://www.youtube.com/watch?v=RaewRYsZHkA

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                                      • Helge_LarsenPI-redaktørH Offline
                                        Helge_LarsenPI-redaktørH Offline
                                        Helge_LarsenPI-redaktør
                                        wrote on sidst redigeret af
                                        #1888

                                        Dejlig video. Tak for den. 🙂

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                                        • SolsenS Offline
                                          SolsenS Offline
                                          Solsen
                                          wrote on sidst redigeret af
                                          #1889

                                          Big big plesant surprice - siger Plessner om immun modulatory effect af dara behandling.

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                                          0

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