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Genmab — Juni 2017

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #1864

    Der peges bl.a. på dara som mulig kombipartner.

    1 Reply Last reply
    0
    • T Offline
      T Offline
      The_Jokers
      wrote on sidst redigeret af
      #1865

      Rookie-spørgsmål her til Genmab-chatten: Ejer Janssen rettighederne til samtlige fremtidige anvendelser af Darzalex eller er det kun MM?

      1 Reply Last reply
      0
      • G Offline
        G Offline
        GeorgeBest
        wrote on sidst redigeret af
        #1866

        Ja,
        Janssen ejer Darzalex i alle indikationer

        1 Reply Last reply
        0
        • T Offline
          T Offline
          The_Jokers
          wrote on sidst redigeret af
          #1867

          Tak. Ved du om Genmab får 20% af alle indtægter så snart det samlede salg når over 3 mia. USD (hvis jeg husker rigtigt) eller er det 3 mia. for hver af de enkelte indikationer?

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          0
          • J Offline
            J Offline
            JKY_VH
            wrote on sidst redigeret af
            #1868

            det må vel være det samlede salg af Dara uanset anvendelsen

            1 Reply Last reply
            0
            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #1869

              EHA is happening now, started
              yesterday https://www.ehaweb.org/congress-and-events/22nd-congress/program-by-day-2/

              1 Reply Last reply
              0
              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #1870

                Bulder , havent read it completely yet, but we have a BCMA CD3 DuoBody in the clinic, right?

                1 Reply Last reply
                0
                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #1871

                  "we" lol

                  1 Reply Last reply
                  0
                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #1872

                    ClinicalTrials.gov

                    favicon

                    (clinicaltrials.gov)

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                    0
                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #1873

                      Jo, men interviewet er let forståeligt for os lægfolk. Og giver indblik i hvordan bispecifikke antistoffer virker.

                      1 Reply Last reply
                      0
                      • SolsenS Offline
                        SolsenS Offline
                        Solsen
                        wrote on sidst redigeret af
                        #1874

                        Look forward to se the first duobody data in human !

                        1 Reply Last reply
                        0
                        • SolsenS Offline
                          SolsenS Offline
                          Solsen
                          wrote on sidst redigeret af
                          #1875

                          Does anyone know when that could happen ?

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                          0
                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #1876

                            ASH 2018?

                            1 Reply Last reply
                            0
                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #1877

                              yes it is Bulder, i saved it for later
                              reading

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                              0
                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #1878

                                Ved nogen om der er planer om at lave en sc-version af JNJ...957?

                                1 Reply Last reply
                                0
                                • G Offline
                                  G Offline
                                  gentogen
                                  wrote on sidst redigeret af
                                  #1879

                                  Could daratumumab be used to treat severe allergy? I Journal of Allergy and Clinical Immunology. Volume 139, Issue 5, May 2017, Pages 1677–1678.e3.

                                  1 Reply Last reply
                                  0
                                  • S Offline
                                    S Offline
                                    Sukkeralf
                                    wrote on sidst redigeret af
                                    #1880

                                    Jan har flere gange tidlige sagt, at Xencor/Amgens CD38/CD3 ikke er vejen frem og Janssen havde noget bedre i støbeskeen. Da Janssen offentliggjorde deres BCMA/CD3 var Celgene vist uden med riven og sige, at det ikke var vejen frem med et bispecifikt antistof mod dette target - og nu er de selv på vej

                                    1 Reply Last reply
                                    0
                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #1881

                                      Vi havde temaet oppe i januar http://www.acsh.org/news/2017/01/30/blood-cancer-drug-could-treat-severe-allergies-10792

                                      1 Reply Last reply
                                      0
                                      • G Offline
                                        G Offline
                                        gentogen
                                        wrote on sidst redigeret af
                                        #1882

                                        Tak

                                        1 Reply Last reply
                                        0
                                        • G Offline
                                          G Offline
                                          gentogen
                                          wrote on sidst redigeret af
                                          #1883

                                          Enhancement of Anti-Tumor Activities of Daratumumab Using ALT-803, an IL-15 Superagonist, in an Experimental Model and Against Primary Human Lymphoma Cells. The Journal of Immunology
                                          Vol. 198, Issue 1 Supplement
                                          1 May 2017

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                                          0

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