Genmab — Maj 2014
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EHA præsentation: Ibrutinib interfererer med terapeutiske CD20-antistoffers cellemedierede antitumor-aktiviteter: implikationer for kombinationsbehandling — Mundtlig præsentation den 15. juni fra 11.00 til 11.15 dansk tid
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de tager nok Gazyva og Arzerra sammen da det er de samme eksperter mv. der skal kigge herpå.
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Ja fedt at de har fået en muntlig præsentation af de prækliniske data hvor de viser Arzerra er bedre end Rituan og Gazyva i Ibrutinib kombi
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In a patient-derived DLBCL model with high (3+) CD38 expression in 80% of tumor cells by IHC, daratumumab in combination with CHOP or R-CHOP showed tumor regression and the tumors did not regrow when the treatment with daratumumab was stopped after 3 doses. The animals were tumor free at the end of the study (day 60) and showed long-term survival compared to daratumumab alone, CHOP alone or R-CHOP alone.
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Ja ville være rigtig fedt hvis vi ser nye studier i DLBLC, FL, CLL, MCL eller lignende med dara i år
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jep. Syntes MCL virker oplagt der. Ibrutinib er allerede godkendt i den indikation som er high unmet need. Kan de tilføre dara til behandlingen og gøre den langt mere effektiv må den ligge til højrebenet
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